478921-20-9Relevant articles and documents
Synthesis and antibacterial activity of 3-substituted-6-(3-ethyl-4- methylanilino)uracils
Zhi, Chengxin,Long, Zheng-Yu,Manikowski, Andrzej,Brown, Neal C.,Tarantino Jr., Paul M.,Holm, Karsten,Dix, Edward J.,Wright, George E.,Foster, Kim A.,Butler, Michelle M.,LaMarr, William A.,Skow, Donna J.,Motorina, Irina,Lamothe, Serge,Storer, Richard
, p. 7063 - 7074 (2007/10/03)
Numerous 3-substituted-6-(3-ethyl-4-methylanilino)uracils (EMAU) have been synthesized and screened for their capacity to inhibit the replication-specific bacterial DNA polymerase IIIC (pol IIIC) and the growth of Gram+ bacteria in culture. Direct alkylat