480-81-9 Usage
Description
Seneciphylline, a pyrrolizidine alkaloid, is a naturally occurring plant toxin and one of the main components of the Chinese medicine herb Tusanqi. It is also a minor constituent of S. jacobaea, a medicinal herb used in Europe. Seneciphylline is known for its effects on coagulation and hemostasis, as well as its potential to affect hepatic drug metabolizing enzymes in rat cells. It is a white crystalline powder, soluble in various organic solvents, and is derived from the whole plant or root of Gynura segetum (Lour.) Merr (Ju Sanqi).
Uses
Used in Traditional Chinese Medicine:
Seneciphylline is used as a medicinal component in traditional Chinese medicine, particularly for its effects on coagulation and hemostasis.
Used in Analytical Chemistry:
Seneciphylline is used as an analytical reference standard for the quantification of the analyte in feed samples and traditional Chinese herbal medicines using different chromatography techniques.
Used in Plant Defense:
Seneciphylline is employed by plants as a natural defense mechanism against herbivore and insect attacks.
Air & Water Reactions
Reacts slowly with atmospheric oxygen. . Insoluble in water.
Reactivity Profile
SENECIPHYLLIN is readily hydrolyzed with alkali; SENECIPHYLLIN reacts readily with oxidizing agents .
Health Hazard
Seneciphylline and aflatoxin B. may be of greater importance as a cause of human disease than the presently known outbreaks of poisoning would indicate.SYMPTOMS: Symptoms associated with this compound include abdominal pain, nausea and diarrhea, emaciation, intestinal edema and congestion of the liver. ACUTE/CHRONIC HAZARDS: Very toxic. (NTP, 1992)
Fire Hazard
Flash point data are not available for SENECIPHYLLIN, but SENECIPHYLLIN is probably combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 480-81-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 0 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 480-81:
(5*4)+(4*8)+(3*0)+(2*8)+(1*1)=69
69 % 10 = 9
So 480-81-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H23NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,14-15,22H,2,6-10H2,1,3H3/b12-4-/t14-,15-,18-/m1/s1
