4810-79-1

Basic information

• Product Name: 4-ISOBUTYL-PYRIDINE
• Synonyms: 4-ISOBUTYL-PYRIDINE;4-(2-Methylpropyl)pyridine;1-Isobutyl-1H-pyrazole-4-carboxylicacid
• CAS NO: 4810-79-1
• Molecular Formula: C₉H₁₃N
• Molecular Weight: 135.21
• EINECS: 225-376-5
• Mol File: 4810-79-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 197-199°C
• Flash Point: 69.2°C
• Appearance: /
• Density: 0.908g/cm³
• Vapor Pressure: 0.468mmHg at 25°C
• Refractive Index: 1.491
• CAS DataBase Reference: 4-ISOBUTYL-PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ISOBUTYL-PYRIDINE(4810-79-1)
• EPA Substance Registry System: 4-ISOBUTYL-PYRIDINE(4810-79-1)

Safety Data

• Hazardous Substances Data: 4810-79-1(Hazardous Substances Data)

Usage

Description

4-Isobutyl-pyridine, with the chemical formula C10H13N, is an organic compound that is a derivative of pyridine. It features a branched isobutyl group attached to the nitrogen atom, which gives it a distinctive strong odor. 4-ISOBUTYL-PYRIDINE is known for its applications across various industries due to its unique properties.

Uses

Used in Food and Beverage Industry:
4-Isobutyl-pyridine is used as a flavoring ingredient for its aromatic qualities, enhancing the taste profiles of various food and drink products.
Used in Perfumes and Personal Care Products:
In the fragrance industry, 4-isobutyl-pyridine serves as a fragrance ingredient, contributing to the creation of complex and appealing scents for perfumes and personal care items.
Used in Antimicrobial Applications:
4-Isobutyl-pyridine has been studied for its potential antimicrobial properties, indicating that it could be utilized in applications where control of microbial growth is necessary.
Used in Insecticidal Applications:
4-ISOBUTYL-PYRIDINE has also demonstrated insecticidal activity, suggesting that it could be employed in products designed to control or repel insects.
It is crucial to handle 4-isobutyl-pyridine with care due to its potential harmful effects if ingested or inhaled, and its ability to cause skin and eye irritation.

InChI:InChI=1/C9H13N/c1-8(2)7-9-3-5-10-6-4-9/h3-6,8H,7H2,1-2H3

Upstream product

• 110-86-1 pyridine 
• 97-72-3 2-Methylpropionic anhydride 
• 108-89-4 picoline 
• 187737-37-7 propene 
• 75-29-6 isopropyl chloride 
• 75-26-3 isopropyl bromide 
• 135351-44-9 2-[2-(2,2-Diethoxy-ethyl)-4-methyl-pentyl]-[1,3]dioxolane 
• 882525-03-3 4-(diisopropoxy-phosphoryl)-4-(1-hydroxy-2-methyl-propyl)-4H-pyridine-1-carboxylic acid ethyl ester 
• 80891-12-9 diisopropyl-1-ethoxycarbonyl-1,4-dihydropyridine-4-phosphonate 
• 542-54-1 isocapronitrile 
• 135351-36-9 2-(2,2-Diethoxy-ethyl)-4-methyl-pentanenitrile 
• 135351-40-5 2-(2,2-Diethoxy-ethyl)-2-[1,3]dioxolan-2-ylmethyl-4-methyl-pentanenitrile 
• 6760-50-5 2-methyl-1-(4-pyridyl)-1-propene 

Downstream Products

• 138761-51-0 4-(1-fluoro-2-methylpropyl)pyridine 

Relevant articles and documents

Efficient Diastereoselective Three-Component Synthesis of Pipecolic Amides

An efficient Ugi-type three-component reaction (U-3CR) for the synthesis of pipecolic amides is reported. The U-3CR between electronically diverse isocyanides, carboxylic acids and 4-substituted Δ1-piperideines proceeds in a highly diastereoselective fashion. The Δ1-piperideines are obtained by NCS-mediated oxidation of the corresponding 4-substituted piperidines, which in turn are generated by an efficient two-step procedure involving the alkylation of 4-picoline and subsequent catalytic hydrogenation of the pyridine ring. We demonstrate the utility of this U-3CR, in combination with the convertible isocyanide 2-bromo-6-isocyanopyridine, in the synthesis of the anticoagulant argatroban.

Regioselective synthesis of 4-alkylpyridines from pyridine and aldehydes via dipole reversal process of 1,4-dihydropyridine phosphonate

4-Alkylation of pyridine has been accomplished by the reaction of ylides, derivated from 1,4-dihydropyridine phosphonate via phosphonioalkoxycarbonylation of pyridine with aldehydes and subsequent elimination of diisopropyl phosphate followed by aromatization with potassium tert-butoxide.

Lincomycin derivatives possessing antibacterial activity

Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.