48172-10-7 Usage
Description
(2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid is an organic compound characterized by its white to light yellow crystalline powder form. It is a derivative of hydroxybutanoic acid with a unique structure that includes a 1,3-dioxoisoindolin-2-yl group attached to the 4-position. (2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid is known for its potential applications in various industries due to its distinct chemical properties.
Uses
Used in Pharmaceutical Industry:
(2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid is used as a key intermediate in the preparation method of plazomicin. Its application in this context is aimed at simplifying the operational process and improving the overall yield of the final product, which is an important antibiotic used to treat various bacterial infections.
Used in Chemical Synthesis:
Due to its unique structure, (2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid can be utilized as a building block in the synthesis of various complex organic molecules. Its reactivity and functional groups make it a valuable component in the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Research and Development:
(2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid's distinctive properties also make it an interesting subject for research and development in the fields of organic chemistry and medicinal chemistry. Scientists and researchers can explore its potential applications in the design of new drugs, materials, and other advanced technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 48172-10-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,8,1,7 and 2 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 48172-10:
(7*4)+(6*8)+(5*1)+(4*7)+(3*2)+(2*1)+(1*0)=117
117 % 10 = 7
So 48172-10-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO5/c14-9(12(17)18)5-6-13-10(15)7-3-1-2-4-8(7)11(13)16/h1-4,9,14H,5-6H2,(H,17,18)/p-1/t9-/m0/s1
48172-10-7Relevant articles and documents
Synthesis method of amikacin intermediate
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Paragraph 0022; 0023, (2019/10/01)
The invention belongs to the field of medicine synthesis, and particularly relates to a synthesis method of an amikacin intermediate. Phthaloyl chloride and 2-hydroxy-4-aminobutyric acid serve as theinitial raw materials, an acid-binding agent and a catalyst are added, the process of heating, washing, recrystallizing and the like is adopted, and finally the target amikacin intermediate product (2-hydroxy-4-phthaloyl iminobutyric acid) is obtained. In the synthesis method, the raw materials are easy to obtain, less reagents participate in the reaction, the steps are simple, operation is convenient, reaction conditions are mind, the product yield is high, and the method is suitable for industrial large-scale production.
DNA sequence selectivity of hairpin polyamide turn units
Farkas, Michelle E.,Li, Benjamin C.,Dose, Christian,Dervan, Peter B.
supporting information; experimental part, p. 3919 - 3923 (2010/03/02)
A class of hairpin polyamides linked by 3,4-diaminobutyric acid, resulting in a β-amine residue at the turn unit, showed improved binding affinities relative to their α-amino-γ-turn analogs for particular sequences. We incorporated β-amino-γ-turns in six-
