483-89-6

Basic information

• Product Name: Benzoic acid,2,3-dimethoxy-6-[2-[4-methoxy-6-[2-(methylamino)ethyl]-1,3-benzodioxol-5-yl]acetyl]-
• Synonyms: Benzoicacid, 2,3-dimethoxy-6-[[4-methoxy-6-[2-(methylamino)ethyl]-1,3-benzodioxol-5-yl]acetyl]-(9CI); Nornarceine (7CI); Nornarcein; Oxynarcotin; Oxynarcotine
• CAS NO: 483-89-6
• Molecular Formula: C22H25 N O8
• Molecular Weight: 431.442
• Mol File: 483-89-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 229 °C (decomp)(Solv: ethanol (64-17-5))
• Boiling Point: 602.9±55.0 °C(Predicted)
• Density: 1.285±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzoic acid,2,3-dimethoxy-6-[2-[4-methoxy-6-[2-(methylamino)ethyl]-1,3-benzodioxol-5-yl]acetyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid,2,3-dimethoxy-6-[2-[4-methoxy-6-[2-(methylamino)ethyl]-1,3-benzodioxol-5-yl]acetyl]-(483-89-6)
• EPA Substance Registry System: Benzoic acid,2,3-dimethoxy-6-[2-[4-methoxy-6-[2-(methylamino)ethyl]-1,3-benzodioxol-5-yl]acetyl]-(483-89-6)

Safety Data

• Hazardous Substances Data: 483-89-6(Hazardous Substances Data)

Usage

Uses

Nornarcein is a derivative of Narcotine (Noscapine: N882000), an antitussive agent.

Upstream product

• 10421-76-8 noscapine 
• 64-19-7 acetic acid 
• 128-62-1 (±)-β-noscapine 
• 128-62-1 noscapine 
• 64-17-5 ethanol 
• 33529-29-2 2,3-dimethoxy-6-(4-methoxy-7-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid; sodium salt 
• 128-62-1 (±)-α-noscapine 

Downstream Products

• 64816-77-9 {2-[6-(3,4-dimethoxy-2-methoxycarbonyl-phenacyl)-7-methoxy-benzo[1,3]dioxol-5-yl]-ethyl}-trimethyl-ammonium; iodide 

Relevant articles and documents

6-(3,4-Methylenedioxy-6-benzylalkylaminoethylphenylacetyl)benzoic acid alkyl ester derivatives

The present invention relates to the preparation of novel rheadan-type alkaloids and to novel intermediates useful in the preparation thereof. The process utilizes as starting materials a known class of alkaloids of the narcotine or of the hydrastine type. Certain of the said novel intermediates are also pharmaceutically useful in and of themselves. Additionally, certain of the novel intermediates can be converted into other type alkaloids which are also pharmaceutically useful.