485842-63-5Relevant articles and documents
A one-pot synthesis of functionalised 3-pyrolin-2-ones by a four-component reaction between triphenylphosphine, primary amines, dimethyl acetylenedicarboxylate and ethyl chlorooxoacetate
Anary-Abbasinejad, Mohammad,Anaraki-Ardakani, Hossein,Dehghan, Alimohammad,Hassanabadi, Alireza,Seyedmir, Mohammad Reza
, p. 574 - 576 (2007)
Reaction between triphenylphosphine, dimethy acetylenedicarboxylate and amines produces phosphorus ylids which undergo a smooth reaction with ethyl chlorooxoacetate and triethylamine to produce dimethyl N-aryl-(or alkyl)-4-ethoxy-5-oxo-2,5-dihydro-1H-pyrole-2,3-dicarboxylates in high yields.