490-64-2Relevant articles and documents
AN OCTAMETHOXYFLAVONE FROM POGOSTEMON PURPURASCENS
Patwardhan, S. A.,Gupta, A. S.
, p. 1458 - 1459 (1981)
3,5,6,7,8,2',4',5'-octamethoxyflavone has been isolated from the whole plant of Pogostemon purpurascens.Key Word Index-Pogostemon purpurascens; Labiatae; purpurascenin; 3,5,6,7,8,2',4',5'-octamethoxyflavone
Synthesis method of pharmaceutical intermediate 2,4,5-trimethoxybenzoic acid
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Paragraph 0008; 0010-0018; 0023; 0024, (2018/09/08)
The invention discloses a synthesis method of a pharmaceutical intermediate 2,4,5-trimethoxybenzoic acid. The synthesis method takes 1,2,4-trimethoxybenzene, DMF (Dimethyl Formamide), phosphoryl chloride, 2,4,5-trimethoxybenzaldehyde, silver nitrate, acetonitrile, hydrogen peroxide, zirconium oxide and MCM-41 as main raw materials, and MCM-41 zeolite powder is subjected to short-chain modificationby adopting tetraethyl orthosilicate TEOS; ultrasonic treatment is carried out on a mixed alkali solution and metal ion frameworks of nickel nitrate and aluminum nitrate are used for replacing to form a unique space three-dimensional framework structure with catalytic activity. According to the synthesis method disclosed by the invention, the disadvantages that products are complicated, the products are difficultly completely purified and the like, caused by drastic oxidization reaction of traditional benzaldehyde, are overcome by an intermediate catalyst, and the intermediate catalyst has anexcellent catalysis effect on synthesis reaction of the 2,4,5-trimethoxybenzoic acid.
Mohr's salt catalyzed oxidation of aldehydes with t-BuOOH
Chakraborty, Debashis,Majumder, Chandrima,Malik, Payal
experimental part, p. 487 - 490 (2012/04/04)
Various aromatic, aliphatic and conjugated aldehydes were transformed to the corresponding carboxylic acids with 70% t-BuOOH solution (water) in the presence of catalytic amounts (10 mol%) of Mohr's salt. This method possesses functional group compatibility, does not involve cumbersome work-up, exhibits chemoselectivity since other functional groups remain intact and proceeds under mild conditions. The resulting products are obtained in good yields within reasonable times. Copyright
Bi2O3-catalyzed oxidation of aldehydes with t-BuOOH
Malik, Payal,Chakraborty, Debashis
supporting information; experimental part, p. 3521 - 3523 (2010/08/22)
A variety of aromatic, aliphatic and conjugated aldehydes were transformed to the corresponding carboxylic acids with 70% t-BuOOH solution (water) in the presence of catalytic amounts of Bi2O3. This method possesses a wide range of capabilities, does not involve cumbersome work-up, exhibits chemoselectivity and proceeds under mild conditions. The resulting products are obtained in good yields within reasonable time. The overall method is green.