492-99-9 Usage
Description
1,2-Cyclohexanedione dioxime, also known as Nioxime, is a beige to brown crystalline powder or needles. It is an analogue of dimethylglyoxime and acts as a chelating ligand, forming complexes with various transition metal ions such as cobalt (Co), iron (Fe), and nickel (Ni). Due to its higher solubility in water compared to dimethylglyoxime, it is widely used in analytical chemistry for the detection and determination of metal ions.
Uses
Used in Analytical Chemistry:
1,2-Cyclohexanedione dioxime is used as an analytical reagent for the detection and determination of nickel and palladium. Its higher solubility in water compared to dimethylglyoxime allows for the precipitation of metal complexes in aqueous solutions, eliminating potential errors caused by increased solubility in the presence of alcohol.
Used in Gravimetric Determinations:
In gravimetric determinations, 1,2-Cyclohexanedione dioxime is used as a chelating agent for the formation of complexes with metal ions, such as nickel. The higher molecular weight of the nioxime complex (340.99 for nickel) compared to the dimethylglyoxime complex (288.91 for nickel) presents an advantage in terms of accuracy and precision.
Used in Photometric Detection of Metal Ions:
1,2-Cyclohexanedione dioxime is used as a chelating ligand in the photometric detection of metal ions. Its ability to form complexes with various transition metal ions, such as cobalt, iron, and nickel, makes it a valuable tool in analytical chemistry for the identification and quantification of these metals.
Used in the Determination of Bismuth:
1,2-Cyclohexanedione dioxime has been successfully applied for the gravimetric determination of bismuth. The bismuth nioxime complex can be precipitated selectively from a solution containing about 30 cations, including nickel and palladium, using the masking action of EDTA at a pH of around 12. This selective precipitation allows for accurate and precise determination of bismuth in complex samples.
Purification Methods
Crystallise Nioxime from alcohol/water and dry it in a vacuum at 40o. Also 2.5g of oxime have been recrystallised from 550mL of H2O using Fe free Norit. It forms complexes with Ni and Pd. [Hach et al. Org Synth 32 35 1952.] [Beilstein 7 IV 1982.]
Check Digit Verification of cas no
The CAS Registry Mumber 492-99-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 2 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 492-99:
(5*4)+(4*9)+(3*2)+(2*9)+(1*9)=89
89 % 10 = 9
So 492-99-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H10N2O2/c9-7-5-3-1-2-4-6(5)8-10/h9-10H,1-4H2/b7-5-,8-6+
492-99-9Relevant articles and documents
Green and highly selective protocol for the synthesis of oximes
Ghosh, Pranab,Subba, Raju
, p. 529 - 532 (2013/11/06)
A green and efficient protocol has been developed for the synthesis of either exclusively a monoxime or exclusively a dioxime from a host of 1,2-dicarbonyl compounds on silica.
Oxidoperoxidotungsten(VI) complexes with secondary hydroxamic acids: Synthesis, structure and catalytic uses in highly efficient, selective and ecologically benign oxidation of olefins, alcohols, sulfides and amines with H2O2 as a terminal oxidant
Maiti, Swarup K.,Dinda, Subhajit,Banerjee, Surajit,Mukherjee, Alok K.,Bhattacharyya, Ramgopal
experimental part, p. 2038 - 2051 (2009/03/11)
The reaction of a solution of freshly precipitated WO3 in H 2O2 separately with the secondary hydroxamic acids N-benzoyl-N-phenylhydroxamic acid (BPHAH), N-benzoyl-Northo-tolylhydroxamic acid (BOTHAH), N-benzoyl-N-meta-tolylhydroxamic acid (BMTHAH), N-benzoyl-N-para- tolyl-hydroxamic acid (BPTHAH) and N-cinnamyl-N-phenylhy-droxamic acid (CPHAH) afforded [WO(O2)(BPHA)2] (1), [WO(O2)(BOTHA) 2] (2), [WO(O2)(BMTHA)2] (3), [WO(O 2)-(BPTHA)2] (4) and [WO(O2)(CPHA)2] (5), respectively. Aqueous tungstate solution, on reaction with all these hydroxamic acids, produced [W(O)2(hydroxamato)2] (6). The complexes show excellent catalytic functions in the oxidation of (a) olefins at room temperature in the presence of NaHCO3 as promoter, (b) alcohols, sulfides and amines, at reflux, with H2O2 as a terminal oxidant, yielding a high turnover number (TON), the highest being for olefin-to-epoxide conversion. An attempt to synthesize peroxide-rich complexes of the type PPh4[WO(O2)2(hydroxamato)] (7), for example PPh4[WO-(O2)2BMTHA] (7C), resulted in the isolation of PPh4[WO-(O2)2(C 6H5COO)] (8), which was probably obtained by the hydrolysis of coordinated BMTHA. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
Kit for the preparation of technetium TC 99m teboroxime myocardial perfusion agent
-
, (2008/06/13)
A kit containing a solution of boronic acid adducts of technetium-99 m dioxime complexes; and hydroxypropyl gamma cyclodextrin to maintain the solution free of particulate matter originating from the formulation.
