493-71-0

Basic information

• Product Name: 2,2-dimethyl-5-phenylfuran-3(2H)-one
• Synonyms: 2,2-Dimethyl-5-phenyl-3(2H)-furanone
• CAS NO: 493-71-0
• Molecular Formula: C₁₂H₁₂O₂
• Molecular Weight: 188.2225
• Mol File: 493-71-0.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 282°C at 760 mmHg
• Flash Point: 120.2°C
• Density: 1.106g/cm³
• Vapor Pressure: 0.00345mmHg at 25°C
• Refractive Index: 1.542
• CAS DataBase Reference: 2,2-dimethyl-5-phenylfuran-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethyl-5-phenylfuran-3(2H)-one(493-71-0)
• EPA Substance Registry System: 2,2-dimethyl-5-phenylfuran-3(2H)-one(493-71-0)

Safety Data

• Hazardous Substances Data: 493-71-0(Hazardous Substances Data)

Usage

Classification

Furanone
A group of organic compounds containing a furan ring.

Appearance

Pale yellow liquid
The visual aspect of the compound in its pure form.

Usage

Synthesis of pharmaceuticals and other organic compounds
The compound serves as a building block or intermediate in creating various medicines and organic substances.

Molecular structure

Furan ring with two methyl groups and a phenyl group attached
The specific arrangement of atoms in the compound, which influences its properties and potential applications.

Biological and pharmacological activities

Antimicrobial and antioxidant properties
The compound has been studied for its potential effects on living organisms, including fighting infections and combating oxidative stress.

Potential applications

Development of new materials and as a flavoring agent in the food industry
The compound may have uses in creating innovative materials or enhancing the taste and aroma of food products.

Research interest

Diverse potential uses and further research and development
The compound's versatility and unique properties make it a valuable subject for ongoing investigation and exploration.

Upstream product

• 25461-80-7 4-methyl-4-hydroxy-1-phenylpent-2-yn-1-one 
• 109-89-7 diethylamine 
• 63678-00-2 4,5-dihydro-2,2-dimethyl-5-phenyl-3(2H)-furanone 
• 15495-23-5 2-hydroxy-2-methyl-5-phenylpent-4-yn-3-one 
• 21478-65-9 3-hydroxy-3-methyl-2-butanone benzoate ester 
• 69626-40-0 4-methyl-1-phenylpenta-2,3-dien-1-one 
• 94815-41-5 2-penten-1-one-3-amino-4-hydroxy-4-methyl-1-phenyl 
• 72795-77-8 4,5-Dibromo-2-hydroxy-2-methyl-5-phenyl-3-pentenone 
• 87064-06-0 Acetic acid 1,1-dimethyl-2-oxo-4-phenyl-but-3-ynyl ester 
• 95511-06-1 1,1-Dimethyl-3-phenyl-2-oxa-6,10-dithia-spiro[4.5]decane 
• 86905-35-3 2-(5-Ethoxy-3-phenyl-4,5-dihydro-isoxazol-5-yl)-propan-2-ol 
• 87064-08-2 (Z)-4-Bromo-1-diethylamino-4-methyl-1-phenyl-pent-1-en-3-one 
• 98-88-4 benzoyl chloride 
• 115-19-5 2-methyl-but-3-yn-2-ol 

Downstream Products

• 5198-65-2 2,2-dimethyl-5-phenyl-furan-3-one-(2,4-dinitro-phenylhydrazone) 
• 84443-08-3 3-hydroxy-2,2-dimethyl-5-phenyl-3-phenylethynyl-2,3-dihydrofuran 
• 84443-10-7 3-hydroxy-2,2-dimethyl-5-phenyl-3-(1-propynyl)-2,3-dihydrofuran 
• 84443-11-8 3-hydroxy-2,2-dimethyl-5-phenyl-3-(t-butylethynyl)-2,3-dihydrofuran 
• 84443-09-4 3-hydroxy-2,2-dimethyl-5-phenyl-3-(p-tolylethynyl)-2,3-dihydrofuran 
• 63838-74-4 2,2-dimethyl-5-phenyl-3-benzoylmethylene-2,3-dihydrofuran 
• 84443-13-0 2,2-dimethyl-5-phenyl-3-acetonylidene-2,3-dihydrofuran 
• 84443-14-1 2,2-dimethyl-5-phenyl-3-(2-oxo-3,3-dimethylbutylidene)-2,3-dihydrofuran 
• 84443-12-9 2,2-dimethyl-5-phenyl-3-(p-toluoylmethylene)-2,3-dihydrofuran 

Relevant articles and documents

Cyclization of α-hydroxy-β-diketones to furan-3(2H)-ones under mild basic conditions

In relation with studies directed to the total synthesis of psuerotin A, conversion of α-hydroxy-β-diketones to the correspponding furan-3(2H)-ones have been successfully performed by a new method using K2CO3 in methanol. Cyclization

Synthesis of a 3(2H)-Furanone Derivative from Propargylic Alcohol, CO, and Phenyl Halide Catalyzed by Transition Metal Complexes

2-Methyl-3-butyn-2-ol reacted with CO and phenyl halides in the presence of a catalytic amount of transition metal complexes to afford 2,2-dimethyl-5-phenyl-3(2H)-furanone (bullatenone) under the influence of CO2.

Synthesis of 5-Aryl-3(2 H)-furanones Using Intramolecular Cyclization of Sulfonium Salts

Base-induced intramolecular cyclization of novel (4-aryl-2,4-dioxobutyl)methylphenylsulfonium salts prepared from the commercially available 1-arylethanone by a cost-effective process is described in this paper. The reaction was completed within 10 min to produce a family of 2-unsubstituted 5-aryl-3(2H)-furanones in excellent yield. This procedure is simple, and can be carried out under mild conditions and an ambient atmosphere.

Synthesis of heterocyclic systems by transition-metal-catalyzed cyclization-migration reactions - A diversity-oriented strategy for the construction of spirocyclic 3(2H)-furanones and 3-pyrrolones

Two platinum(II)-catalyzed heterocyclization-migration reactions that provide five-membered heterocycle products are described. With 5 mol-% of PtCl2 as a catalyst, 2-alkynyl-2-hydroxy carbonyl compounds 1 are converted into 3(2H)-furanones 2 a