497833-00-8 Usage
Description
1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole is a pyrazole derivative, a class of organic compounds with a five-membered heterocyclic ring. This specific compound is characterized by the presence of a bromine atom attached to a phenyl ring and a trifluoromethyl group attached to the pyrazole ring. Its unique structure and chemical properties make it a promising candidate for various applications in pharmaceuticals, agrochemicals, and materials science. Additionally, it may exhibit interesting biological and pharmacological activities, warranting further research and development in multiple fields.
Uses
Used in Pharmaceutical Industry:
1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole is used as a building block for the development of new pharmaceutical compounds due to its unique structure and potential biological and pharmacological activities. Its ability to interact with various biological targets makes it a valuable asset in the design and synthesis of novel drugs.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole is used as a key intermediate in the synthesis of various agrochemical products. Its unique chemical properties allow for the development of new compounds with improved efficacy and selectivity in pest control and crop protection.
Used in Materials Science:
1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole is utilized as a component in the development of advanced materials with specific properties. Its unique structure and chemical properties can contribute to the creation of materials with enhanced performance in various applications, such as electronics, coatings, and adhesives.
Overall, 1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole is a versatile compound with potential applications across multiple industries, including pharmaceuticals, agrochemicals, and materials science. Its unique structure and chemical properties make it an attractive candidate for further research and development, with the aim of unlocking its full potential in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 497833-00-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,7,8,3 and 3 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 497833-00:
(8*4)+(7*9)+(6*7)+(5*8)+(4*3)+(3*3)+(2*0)+(1*0)=198
198 % 10 = 8
So 497833-00-8 is a valid CAS Registry Number.
497833-00-8Relevant articles and documents
Switchable reactivity: The site-selective functionalization of trifluoromethyl-substituted pyrazoles
Schlosser, Manfred,Volle, Jean-Noel,Leroux, Frederic,Schenk, Kurt
, p. 2913 - 2920 (2002)
Modern organometallic methods enable the regioflexible conversion of simple heterocyclic starting materials into families of isomers and congeners. Depending on the choice of the reagent, 1-methyl-5-(trifluoromethyl)pyrazole (1) undergoes deprotonation and subsequent carboxylation mainly or exclusively at either the 4-position of the heterocycle or at the nitrogen-attached methyl group. Similarly, 1-phenyl-5-(trifluoromethyl)pyrazole (5) and 3-methyl-l-phenyl-5-(trifluoromethyl)pyrazole (8) are selectively attacked by lithium diisopropylamide at the heterocyclic 4-position and by butyllithium concomitantly at the 4-position and the ortho position of the phenyl ring. In contrast, metalation of 1-methyl-3-(trifluoromethyl)pyrazole (2) occurs only at the 5-position, whatever the organometallic or metal amide base. Further sites become accessible to functionalization if bromine is introduced into the heterocyclic or aromatic ring. This has been demonstrated with 4-bromo-1-methyl-5-(trifluoromethyl)pyrazole (3), 4-bromo-l-methyl-3-(trifluoromethyl)pyrazole (4), 4-bromo-1-methyl-5-(trifluoromethyl)pyrazole (7) and 1-(2-bromophenyl)-5-(trifluoromethyl)pyrazole (6). Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.
