4989-36-0Relevant articles and documents
Cytoprotective effects of hydrogen sulfide-releasing N-methyl-d-aspartate receptor antagonists mediated by intracellular sulfane sulfur
Marutani, Eizo,Sakaguchi, Masahiro,Chen, Wei,Sasakura, Kiyoshi,Liu, Jifeng,Xian, Ming,Hanaoka, Kenjiro,Nagano, Tetsuo,Ichinose, Fumito
, p. 1577 - 1583 (2014)
Hydrogen sulfide (H2S) exerts a host of biological effects ranging from cytotoxicity to cytoprotection. Cytotoxicity of H2S in neurodegenerative diseases may be mediated by N-methyl-d-aspartate receptor (NMDAR) activation. To exploit
H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance
Chegaev, Konstantin,Rolando, Barbara,Cortese, Daniela,Gazzano, Elena,Buondonno, Ilaria,Lazzarato, Loretta,Fanelli, Marilù,Hattinger, Claudia M.,Serra, Massimo,Riganti, Chiara,Fruttero, Roberta,Ghigo, Dario,Gasco, Alberto
supporting information, p. 4881 - 4889 (2016/06/13)
Doxorubicin (DOXO) is one of the most effective antineoplastic agents in clinical practice. Its use is limited by acute and chronic side effects, in particular by its cardiotoxicity and by the rapid development of resistance to it. As part of a program ai
A mild and versatile synthesis of thioamides
Mahammed,Jayashankara,Premsai Rai,Mohana Raju,Arunachalam
experimental part, p. 2338 - 2340 (2009/12/08)
Aliphatic and aromatic nitriles react with thioacetic acid in the presence of calcium hydride to give the corresponding thioamides in good to excellent yields. The examples studied include haloaryl nitriles in which the halogen is facile towards SNAr reactions under other conditions. Georg Thieme Verlag Stuttgart.
