500695-43-2Relevant articles and documents
Synthesis and biological activity of novel neuroprotective diketopiperazines.
Prakash,Tang,Kozikowski, Alan P,Flippen-Anderson, Judith L,Knoblach, Susan M,Faden, Alan I
, p. 3043 - 3048 (2007/10/03)
The cyclic dipeptide cyclo[His-Pro] (CHP) is synthesized endogenously de novo and as a breakdown product of thyrotropin-releasing hormone (TRH), a tripeptide with known neuroprotective activity. We synthesized two isomeric compounds based on the structure