500736-32-3Relevant articles and documents
Structural modification of an angiogenesis inhibitor discovered from traditional chinese medicine and a structure-activity relationship study
Yang, Sheng-Ping,Cai, Yu-Jun,Zhang, Bang-Le,Tong, Lin-Jiang,Xie, Hua,Wu, Yan,Lin, Li-Ping,Ding, Jian,Yue, Jian-Min
, p. 77 - 85 (2008)
Pseudolaric acid B (PAB), discovered as a promising angiogensis inhibitor, was served as the anticancer drug lead, and a series of its derivatives were synthesized. Among them, some derivatives, such as 13c-13k, exhibited potent inhibition on the HMEC-1 c