501083-26-7

Basic information

• Product Name: C₅₅H₆₆Cl₂N₆O₉
• Synonyms: C₅₅H₆₆Cl₂N₆O₉
• CAS NO: 501083-26-7
• Molecular Weight: 1026.07
• Mol File: 501083-26-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₅H₆₆Cl₂N₆O₉(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₅H₆₆Cl₂N₆O₉(501083-26-7)
• EPA Substance Registry System: C₅₅H₆₆Cl₂N₆O₉(501083-26-7)

Safety Data

• Hazardous Substances Data: 501083-26-7(Hazardous Substances Data)

Upstream product

• 501083-17-6 estrone-3-O-CH₂CO-Tyr(2,6-dichlorobenzyl)-Gly-Gly-Phe-Leu-NH₂ 
• 687-51-4 H-L-Leu-NH₂ 
• 53-16-7 Estrone 
• 41164-32-3 3-ethyloxycarbonylmethylenoxyestrone 
• 1428-66-6 2-(((8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl)oxy)acetic acid 
• 183670-74-8 H-Tyr(DCB)-Gly-Gly-Phe-Leu-NH₂ 
• 501082-80-0 Boc-Tyr(2,6-Cl₂Bzl)-Gly-Gly-Phe-Leu-NH₂ 
• 501082-72-0 Boc-Tyr(2,6-Cl₂Bzl)-Gly-Gly-Phe-OH 
• 501082-71-9 Boc-Tyr(2,6-Cl₂Bzl)-Gly-Gly-Phe-OMe 

Relevant articles and documents

Studies on the synthesis of estrogen-GHRPS linkers

A series of linkers consisted of estrone, estradiol, and GHRPS (growth hormone releasing peptides) were prepared with carboxyl-methyl or succinyl as the conjugated group. As a protective group in the side chain of Tyr, the Dcb (2,6-dichlorobenzyl) in the intermediates which is unstable to HF can be removed in high yield in the presence of Pd/C (10%), H2, and 4.4% formic acid in methanol.