5018-87-1

Basic information

• Product Name: 2-(NAPHTHOYL)BENZOIC ACID
• Synonyms: 2-(1-Naphthalenylcarbonyl)benzoic acid;2-(naphthalene-1-carbonyl)benzoic acid;2-naphthalen-1-ylcarbonylbenzoic acid
• CAS NO: 5018-87-1
• Molecular Formula: C₁₈H₁₂O₃
• Molecular Weight: 276.29
• EINECS: 225-702-6
• Mol File: 5018-87-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 525.8°Cat760mmHg
• Flash Point: 285.9°C
• Appearance: /
• Density: 1.289g/cm³
• Vapor Pressure: 6.96E-12mmHg at 25°C
• Refractive Index: 1.678
• CAS DataBase Reference: 2-(NAPHTHOYL)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(NAPHTHOYL)BENZOIC ACID(5018-87-1)
• EPA Substance Registry System: 2-(NAPHTHOYL)BENZOIC ACID(5018-87-1)

Safety Data

• Hazardous Substances Data: 5018-87-1(Hazardous Substances Data)

Usage

General Description

2-(Naphthoyl)benzoic acid is a chemical compound with the molecular formula C19H14O3. It is a white to light yellow crystalline powder that is sparingly soluble in water. 2-(NAPHTHOYL)BENZOIC ACID is used as a fluorescent probe and as a ligand for metal ion complexes. It is also used in the synthesis of organic compounds and pharmaceuticals. The 2-(naphthoyl)benzoic acid has potential applications in the field of material science, pharmacology and chemical research due to its unique chemical properties and reactivity.

InChI:InChI=1/C18H12O3/c19-17(15-9-3-4-10-16(15)18(20)21)14-11-5-7-12-6-1-2-8-13(12)14/h1-11H,(H,20,21)

Upstream product

• 85-44-9 phthalic anhydride 
• 91-20-3 naphthalene 
• 703-55-9 1-naphthylmagnesiumbromide 
• 71-43-2 benzene 
• 7446-70-0 aluminium trichloride 
• 605-02-7 1-phenylnaphthalene 
• 30247-86-0 2-(chlorocarbonyl)benzoic acid 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 1821-12-1 4-Phenylbutyric acid 
• 2051-95-8 succinylbenzene 
• 90-11-9 1-Bromonaphthalene 

Downstream Products

• 299927-96-1 2-[1]naphthoyl-benzoic acid methyl ester 
• 78772-71-1 3-methyl-3-(1-naphthyl)-2-benzofuran-1(3H)-one 
• 2498-66-0 benz[a]anthracene-7,12-dione 
• 107733-24-4 3-naphthalen-1-yl-3H-isobenzofuran-1-one 
• 4658-06-4 pleiadene-5,12-dione 
• 69238-67-1 o-<(1-naphthyl)methyl>benzoic acid 
• 57835-94-6 4-(1-naphthyl)phthalaz-1-one 
• 5018-89-3 2-(5-chloro-[1]naphthoyl)-benzoic acid 
• 6324-57-8 2-(5-bromo-[1]naphthoyl)-benzoic acid 
• 72872-62-9 o,o'-benzil dicarboxylic acid 
• 15394-60-2 N-(α-Naphthoyl)anthranilic acid 
• 118658-73-4 2-(5,6,7,8-tetrahydro-1-naphtoyl)benzoic acid 
• 873388-31-9 2-(5,8-dichloro-[1]naphthoyl)-benzoic acid 
• 91-20-3 naphthalene 

Relevant articles and documents

Mechanochemical Friedel-crafts acylations

Friedel-Crafts (FC) acylation reactions were exploited in the preparation of ketone-functionalized aromatics. Environmentally more friendly, solvent-free mechanochemical reaction conditions of this industrially important reaction were developed. Reaction parameters such as FC catalyst, time, ratio of reagents and milling support were studied to establish the optimal reaction conditions. The scope of the reaction was explored by employment of different aromatic hydrocarbons in conjunction with anhydrides and acylation reagents. It was shown that certain FC-reactive aromatics could be effectively functionalized by FC acylations carried out under ball-milling conditions without the presence of a solvent. The reaction mechanism was studied by in situ Raman and ex situ IR spectroscopy.

Synthesis, Structure, and Properties of Tetrabenzo[7]circulene

Tetrabenzo[7]circulene, a new member of aromatic saddles, was conveniently synthesized from 2-(1-naphthoyl)benzoic acid with the seven-membered ring constructed at an early stage of the synthesis. This method, upon minor modification, was also useful for synthesis of thiophene-annulated [7]circulenes. The structures of tetrabenzo[7]circulene and [7]circulene were compared in terms of symmetry, flexibility, and curvature on the basis of DFT calculations and X-ray crystallography. It was also found that tetrabenzo[7]circulene functioned as a p-type semiconductor in thin-film transistors and cocrystallized with C60

Direct synthesis of γ-substituted phthalides by cyclization of benzyl radicals generated from o-(arylmethyl)benzoic acids

Direct oxidation of o-(arylmethyl)benzoic acids with sodium peroxysulfate-copper(II) chloride in water yields γ-substituted phthalides. The reaction is highly regioselective, and the corresponding γ-butyro-lactones are the only products formed through intermediate stable arylmethyl radicals.