502482-44-2

Basic information

• Product Name: 1-N-BOC-4-N-BENZYL-2-ETHYL PIPERAZINE
• Synonyms: 1-N-BOC-4-N-BENZYL-2-ETHYL PIPERAZINE;(S)-TERT-BUTYL 4-BENZYL-2-ETHYLPIPERAZINE-1-CARBOXYLATE;TERT-BUTYL-2-ETHYL-4-BENZYL-1-PIPERAZINECARBOXYLATE
• CAS NO: 502482-44-2
• Molecular Formula: C₁₈H₂₈N₂O₂
• Molecular Weight: 304.43
• Mol File: 502482-44-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 386.5°C at 760 mmHg
• Flash Point: 187.6°C
• Appearance: /
• Density: 1.043g/cm³
• Vapor Pressure: 3.52E-06mmHg at 25°C
• Refractive Index: 1.521
• CAS DataBase Reference: 1-N-BOC-4-N-BENZYL-2-ETHYL PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-BOC-4-N-BENZYL-2-ETHYL PIPERAZINE(502482-44-2)
• EPA Substance Registry System: 1-N-BOC-4-N-BENZYL-2-ETHYL PIPERAZINE(502482-44-2)

Safety Data

• Hazardous Substances Data: 502482-44-2(Hazardous Substances Data)

Usage

Purpose

Used in the synthesis of pharmaceutical drugs and as a reagent in organic chemistry.

Classification

Piperazine derivative.

Protecting group

BOC (tert-butyloxycarbonyl) group at the 1-N position.

Substituent

Benzyl group at the 4-N position.

Building block

Acts as a building block in the synthesis of various medical drugs.

Pharmaceutical intermediates

Used to prepare various types of pharmaceutical intermediates.

Versatility

Utilized in research laboratories for organic synthesis due to its versatile chemical properties.

Reactivity

Ability to react with a variety of other compounds.

InChI:InChI=1/C18H28N2O2/c1-5-16-14-19(13-15-9-7-6-8-10-15)11-12-20(16)17(21)22-18(2,3)4/h6-10,16H,5,11-14H2,1-4H3/t16-/m0/s1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 324750-04-1 (3S)-1-benzyl-3-ethylpiperazine 
• 6436-90-4 ethyl 2-(benzylamino)acetate 
• 325145-36-6 (3S)-3-ethyl-1-(phenylmethyl)-2,5-piperazinedione 

Downstream Products

• 325145-35-5 (S)-2-ethylpiperazine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Novel Compounds

The invention relates to substituted aryl acids as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.

PIPERAZINE UREA DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS

Certain novel piperazine urea derivatives are agonists of the human melanocortin-4 receptor (MC-4R) and, in particular, are receptor-subtype selective agonists of MC-4R. They are useful for the treatment, control, or prevention of diseases and disorders r

2-Substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyltransferase [1]

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