50353-64-5

Basic information

• Product Name: 1-(4-n-hexyloxyphenyl)-2-(4'-hydroxyphenyl)acetylene
• Synonyms: 1-(4-n-hexyloxyphenyl)-2-(4'-hydroxyphenyl)acetylene
• CAS NO: 50353-64-5
• Molecular Weight: 294.393
• Mol File: 50353-64-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(4-n-hexyloxyphenyl)-2-(4'-hydroxyphenyl)acetylene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-n-hexyloxyphenyl)-2-(4'-hydroxyphenyl)acetylene(50353-64-5)
• EPA Substance Registry System: 1-(4-n-hexyloxyphenyl)-2-(4'-hydroxyphenyl)acetylene(50353-64-5)

Safety Data

• Hazardous Substances Data: 50353-64-5(Hazardous Substances Data)

Upstream product

• 30752-19-3 1-bromo-4-hexyloxylbenzene 
• 111-25-1 1-bromo-hexane 
• 88075-18-7 4-(2-(trimethylsilyl)ethynyl)phenol 
• 85557-94-4 1-iodo-4-hexyloxybenzene 
• 182412-16-4 1-hexyloxy-4-[2-(trimethylsilyl)ethynyl]benzene 
• 540-38-5 p-Iodophenol 
• 115-19-5 2-methyl-but-3-yn-2-ol 

Relevant articles and documents

Phenoxide-mediated Sonogashira coupling of trimethylsilylalkynes and aryliodides: Practical synthesis of phenolic-hydroxy-substituted diarylethynes and 1,4-diarylbutadiynes

We successfully synthesized phenolic-hydroxy-substituted diarylethynes and 1,4-diarylbutadiynes from trimethylsilylalkynes and aryliodides via silyl-group-migration-induced deprotection of alkynes and the usual Sonogashira coupling. The phenol moiety, which works as a desilylating agent, can be attached to any position in the coupling partner. This improvement for Sonogashira coupling would be highly effective, especially when the coupling partner has a phenol moiety. Additionally, the stability of the migrated silyl moiety on the ethynylation of 2-iodophenol is discussed.

Nematic Tolans.

Eighteen p p prime disubstituted tolans have been synthesized in the three following series: 1. p alkoxy p prime alkanoate, 2. p p prime dialkanoate, 3. p-alkoxy p prime alkylcarbonate tolans. All are nematic except those of series 2. They are compared with some other tolans. The p alkoxy p prime alkyl and p p prime alkoxy tolans. Values of temperature transitions and sign of dielectric anisotropy ( DELTA epsilon ) appear to be bound to the nature of the functional p substituted groups. Moreover, evolution of the mesomorphic temperature range with carbons number is studied for p alkoxy p prime alkanoate tolans.