5043-05-0

Basic information

• Product Name: 2-Naphthalenecarboxylic acid, 6-(dimethylamino)-
• CAS NO: 5043-05-0
• Molecular Formula: C13H13NO2
• Molecular Weight: 215.252
• Mol File: 5043-05-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Naphthalenecarboxylic acid, 6-(dimethylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Naphthalenecarboxylic acid, 6-(dimethylamino)-(5043-05-0)
• EPA Substance Registry System: 2-Naphthalenecarboxylic acid, 6-(dimethylamino)-(5043-05-0)

Safety Data

• Hazardous Substances Data: 5043-05-0(Hazardous Substances Data)

Usage

General Description

2-Naphthalenecarboxylic acid, 6-(dimethylamino)- is a chemical compound that belongs to the class of naphthalene carboxylic acids. 2-Naphthalenecarboxylic acid, 6-(dimethylamino)- is a derivative of naphthalene and contains a carboxylic acid group as well as a dimethylamino group. It is used in various medical and research applications as a fluorescent dye and as a precursor for the synthesis of other compounds. It is also utilized in the preparation of pharmaceuticals and as a pH indicator in chemical reactions. This chemical has the potential for use in the development of new medications and in various biochemical studies.

Upstream product

• 67-56-1 methanol 
• 116668-47-4 6-amino-2-naphthoic acid 
• 124-38-9 carbon dioxide 
• 5043-03-8 6?bromo?N,N?dimethylnaphthalen?2?amine 
• 50-00-0 formaldehyd 
• 91-59-8 naphthalen-2-ylamine 
• 13720-04-2 1,6-dibromonaphthalen-2-amine 
• 7499-66-3 6-Bromonaphthalen-2-amine 
• 58601-32-4 6-methoxy-2-naphthoyl chloride 
• 2471-70-7 2-methoxy-6-naphthoic acid 
• 159429-50-2 2-(6-methoxy-naphthalen-2-yl)-4,4-dimethyl-4,5-dihydro-oxazole 
• 68520-00-3 1-(6-(dimethylamino)naphthalen-2-yl)ethan-1-one 
• 5043-04-9 2-(dimethylamino)-6-naphthonitrile 

Downstream Products

• 5043-06-1 methyl 6-(dimethylamino)-2-naphthoate 
• 891491-99-9 6-(dimethylamino)naphthalene-2-methanol 
• 872419-13-1 6-Dimethylamino-naphthalene-2-carboxylic acid (2-{9-{(2R,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-[2-(4-nitro-phenyl)-ethoxy]-9H-purin-2-ylamino}-ethyl)-amide 
• 872419-08-4 6-Dimethylamino-naphthalene-2-carboxylic acid [2-(1-{(2R,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-2-oxo-1,2-dihydro-pyrimidin-4-ylamino)-ethyl]-amide 
• 872419-12-0 6-Dimethylamino-naphthalene-2-carboxylic acid (2-{9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-[2-(4-nitro-phenyl)-ethoxy]-9H-purin-2-ylamino}-ethyl)-amide 
• 872419-11-9 6-dimethylamino-naphthalene-2-carboxylic acid (2-{9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-6-[2-(4-nitro-phenyl)-ethoxy]-9H-purin-2-ylamino}-ethyl)-amide 
• 742106-44-1 methyl 4-({[6-(dimethylamino)-2-naphthoyl]amino}methyl)benzoate 

Relevant articles and documents

A benzothioate native chemical ligation-based cysteine-selective fluorescent probe

A turn-on fluorescent probe for the detection of cysteine (Cys), an essential amino acid in biological systems, is developed based on Cys-mediated O-phenyl benzothioate native chemical ligation (NCL) for the first time. Cys plays important roles in many p

An uridine derivative containing a hydrophobic fluorescent probe at the 2'-position: Synthesis and its incorporation into oligonucleotides

The synthesis of 2'-(6-dimethylamino-2-naphthamide)uridine [U(DAN)] has been described. The nucleoside was converted to the 5'-dimethoxytrityl nucleoside phosphoramidite which could be used for incorporation of U(DAN) into the desired positions of the oligonucleotide sequence.

Two-photon ratiometric fluorescent probe compound for detecting aminopeptidase N, and preparation method thereof

The invention discloses a preparation method of a two-photon ratiometric fluorescent probe compound for detecting aminopeptidase N. The structure of the fluorescent compound is represented by formulaI. The probe compound is designed based on the principle of fluorescence resonance energy transfer, a two-photon naphthalene derivative is selected as an energy donor, a p-methylaminophenol fluorophore is used as an energy acceptor, and alanine is introduced as an aminopeptidase N specific recognition unit. The aminopeptidase N is used to preferentially hydrolyze an N-terminal alanyl group, whichcauses the proportional change in a fluorescence emission signal. The compound has the advantages of high sensitivity, high selectivity, large emission shift, and quickness in detection of the aminopeptidase N, can be successfully applied to two-photon fluorescence imaging in living cells and tissues, and provides a potential tool for clinical detection of kidney injuries.