50434-36-1

Basic information

• Product Name: 2-(4-nitrophenyl)acetyl chloride
• Synonyms: 2-(4-nitrophenyl)acetyl chloride
• CAS NO: 50434-36-1
• Molecular Formula: C₈H₆ClNO₃
• Molecular Weight: 199.59
• Mol File: 50434-36-1.mol
• Article Data: 98

Chemical Properties

• Boiling Point: 328.9 °C at 760 mmHg
• Flash Point: 152.7 °C
• Appearance: /
• Density: 1.399 g/cm³
• Vapor Pressure: 0.000183mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: 2-(4-nitrophenyl)acetyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-nitrophenyl)acetyl chloride(50434-36-1)
• EPA Substance Registry System: 2-(4-nitrophenyl)acetyl chloride(50434-36-1)

Safety Data

• Hazardous Substances Data: 50434-36-1(Hazardous Substances Data)

Usage

Description

2-(4-nitrophenyl)acetyl chloride is an organic compound that consists of a 4-nitrophenyl group attached to an acetyl chloride moiety. It is a versatile reagent in organic synthesis and has unique chemical properties due to the presence of both the aromatic ring and the acetyl chloride functional group.

Uses

Used in Organic Synthesis:
2-(4-nitrophenyl)acetyl chloride is used as a reactant or starting material for the preparation of artificial receptors. Its reactivity and the presence of the nitro group make it a valuable building block in the synthesis of complex organic molecules, particularly those with potential applications in supramolecular chemistry and molecular recognition.
Used in Chemical Research:
In the field of chemical research, 2-(4-nitrophenyl)acetyl chloride is utilized as a reagent to study reaction mechanisms and to develop new synthetic methodologies. Its unique structure allows chemists to explore various reaction pathways and to gain insights into the fundamental aspects of organic chemistry.
Used in Pharmaceutical Industry:
2-(4-nitrophenyl)acetyl chloride is also used in the pharmaceutical industry as an intermediate in the synthesis of various drug candidates. Its ability to form stable acylating agents makes it suitable for the preparation of biologically active compounds with potential therapeutic applications.
Used in Material Science:
In material science, 2-(4-nitrophenyl)acetyl chloride can be employed in the development of new materials with specific properties. For instance, it can be used to create functional polymers or to modify the surface properties of materials for various applications, such as sensors, catalysts, or coatings.

InChI:InChI=1/C8H6ClNO3/c9-8(11)5-6-1-3-7(4-2-6)10(12)13/h1-4H,5H2

Upstream product

• 104-03-0 4-nitrobenzeneacetic acid 
• 140-29-4 phenylacetonitrile 
• 555-21-5 4-Nitrophenylacetonitrile 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 21443-39-0 1-diazo-3-(4-nitro-phenyl)-propan-2-one 
• 16036-11-6 (4-nitro-phenyl)-acetic acid-(4-hydroxy-anilide) 
• 16036-10-5 (4-nitro-phenyl)-acetic acid p-anisidide 
• 100725-78-8 S-phenyl 2-(4-nitrophenyl)ethanethioate 
• 53218-12-5 p-Nitrophenylessigsaeure-(m-tolylester) 
• 20765-22-4 1-(4-methoxyphenyl)-2-(4-nitrophenyl)ethanone 
• 92164-88-0 (4-nitro-phenyl)-acetic acid-(4-nitro-anilide) 
• 90405-67-7 N,N-dimethyl-2-(4-nitrophenyl)acetamide 
• 251643-21-7 N-(N',N'-Dimethylaminoethyl) 4-nitrophenylacetamide 
• 100117-02-0 (4-nitro-phenyl)-acetic acid-[bis-(2-chloro-ethyl)-amide] 
• 109442-93-5 (4-nitro-phenyl)-thioacetic acid S-(4-chloro-phenyl ester) 

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