5044-27-9Relevant articles and documents
A convenient approach for the synthesis of substituted pyrroles by using phosphoric acid as a catalyst and their photophysical properties
Ai, Liankun,Ibrahim, Yusuf Ajibola,Li, Baolin,Li, Jiahui
, (2021/12/21)
Twenty-three new pyrrole compounds aside from six knowns, including the synthetically challenging tetra- and penta-substituted pyrroles from the corresponding 1,4-dicarbonyl through Paal-Knorr synthesis in the presence of 5% phosphoric acid as the catalyst. Our method is noteworthy for cheap catalyst, uncomplicated experimental setup under air atmosphere, scalability, and excellent yields. The fluorescence of some selected pyrroles was investigated in dilute solution, and we found that all novel pyrroles emit strong blue fluorescences with considerable Stokes shifts.
Facile fabrication of porous magnetic covalent organic frameworks as robust platform for multicomponent reaction
Azizi, Najmedin,Heidarzadeh, Fatemeh,Farzaneh, Fezeh
, (2021/07/26)
The design of cheap yet efficient nanoporous magnetic catalysts for the environmentally benign process's widespread application is an extremely attractive, challenging chemical research field. A novel porous magnetic covalent organic framework was prepared by the condensation reaction of melamine and terephthaladehyde on the surface of 3,4-dihydroxybenzaldehyde coated magnetic Fe3O4 nanoparticles COF@Fe3O4 under hydrothermal conditions for the first time. The high surface area magnetic COF could exhibit superior catalytic activity for sustainable synthesis of trisubstituted and tetrasubstituted imidazoles and pyrroles in good to excellent yields in PEG as solvent under environmentally friendly, ambient conditions and making the overall process economical, efficient, and green. The retrievable catalyst in PEG is general and applicable to a broad substrate scope and functional group compatibility. The structure and morphology of the COF@Fe3O4 were characterized by FTIR, XRD, EDX, and SEM spectroscopy. The COF@Fe3O4 magnetic catalyst was recovered by an external magnet and used for several cycles without significant catalytic activity loss.
Preparation method of biomass-based 2, 5-dimethyl-N-substituted pyrrole derivative
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Paragraph 0055-0057, (2021/07/14)
The invention discloses a preparation method of a biomass-based 2, 5-dimethyl-N-substituted pyrrole derivative. The method comprises the following steps: adding 2, 5-dimethylfuran, an amine compound, a catalyst, distilled water and 2mL of solvent into a reaction kettle, and heating the reaction kettle in an oil bath pan; and obtaining the 2, 5-dimethyl-N-substituted pyrrole derivative after the temperature is 110-170 DEG C, the use amount of distilled water is 0-250 [mu] L, the use amount of the catalyst is 5-10 wt%, and the reaction time is 1-3 h. The method overcomes the defects of high cost and difficulty in separation and recovery of the existing catalyst or catalyst system.
