50558-21-9 Usage
Description
2-Chlorobiphenylene, also known as 2-chloro-1,1'-biphenyl, is a chlorinated aromatic hydrocarbon compound with a molecular formula of C12H9Cl. It is characterized by the presence of one chlorine atom attached to a biphenyl molecule, which consists of two phenyl rings connected by a carbon-carbon bond. 2-CHLOROBIPHENYLENE is known for its potential environmental and health impacts due to its persistence and bioaccumulation properties.
Uses
Used in Environmental Testing and Research:
2-Chlorobiphenylene serves as a standard for environmental testing and research, particularly in the analysis of persistent organic pollutants (POPs) and their effects on ecosystems and human health. It is used to develop and validate analytical methods for the detection and quantification of similar chlorinated compounds in various environmental matrices, such as air, water, and soil.
Used in Toxicological Studies:
2-Chlorobiphenylene exhibits a chlorinated biphenylenes structure-dependent effect on the aryl hydrocarbon (Ah) receptor and cytochrome P450 (CYP) enzymes. It is used in toxicological studies to investigate the molecular mechanisms underlying the toxic effects of chlorinated biphenyls and their potential role in the development of various diseases, including cancer and endocrine disruption.
Used in Chemical Synthesis:
2-Chlorobiphenylene can also be used as a starting material or intermediate in the synthesis of various organic compounds, such as pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure and reactivity make it a valuable building block for the development of new molecules with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 50558-21-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,5,5 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 50558-21:
(7*5)+(6*0)+(5*5)+(4*5)+(3*8)+(2*2)+(1*1)=109
109 % 10 = 9
So 50558-21-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H7Cl/c13-8-5-6-11-9-3-1-2-4-10(9)12(11)7-8/h1-7H
50558-21-9Relevant articles and documents
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Losey,E.N.,LeGoff,E.
, p. 3812 (1973)
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Synthesis of Biphenylenes and Their Higher Homologues by Cyclization of Aryne Derivatives
Wang, Sheng-Li,Pan, Ming-Lun,Su, Wei-Siang,Wu, Yao-Ting
, p. 14694 - 14697 (2017/10/23)
This investigation demonstrates that a series of biphenylenes can be easily prepared from their corresponding halobiphenyls by the cyclization of in situ generated 2′,3′-didehydro-2-lithiobiphenyls at low temperature. Two remarkable advantages of this synthetic method include 1) the lack of any need for transition-metal catalysts or reagents in the cyclization, and 2) the ability to obtain C1-functionalized products by treating the reaction intermediate 1-lithiobiphenylene with an electrophilic reagent. π-Extended derivatives, such as benzobiphenylenes, dibenzobiphenylene, linear/angular [3]phenylenes, and biphenyleno[2,3-b]biphenylenes, were synthesized similarly using suitable biaryls or teraryls.
