50564-17-5Relevant articles and documents
Facile synthesis of [11C]edrophonium and its analogues as new potential PET imaging agents for heart acetylcholinesterase
Zheng, Qi-Huang,Liu, Xuan,Fei, Xiangshu,Wang, Ji-Quan,Mock, Bruce H.,Glick-Wilson, Barbara E.,Sullivan, Michael L.,Hutchins, Gary D.
, p. 1787 - 1790 (2003)
[11C]Edrophonium and its analogues have been synthesized for evaluation as new potential positron emission tomography (PET) imaging agents for heart acetylcholinesterase. The tracers were prepared by N-[11C]methylation of precursors
ACYL SULFONAMIDES FOR TREATING CANCER
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Page/Page column 279, (2020/11/03)
The present invention provides acyl sulfonamide compounds of general formula (I): in which X, R1, R2, R3, R4, R5, R6, Ra and Rb are as described and defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients as well as methods of treating and/or prophylaxing diseases, particularly cancer, more particularly cancer in which KAT6A and/or KAT6B is focally amplified, said method comprising administering an effective amount of at least one compound of formula (I) to a subject in need thereof.