50704-04-6

Basic information

• Product Name: 2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-2-methyl-, methyl ester, (2E)-
• CAS NO: 50704-04-6
• Molecular Formula: C13H17NO2
• Molecular Weight: 219.283
• Mol File: 50704-04-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-2-methyl-, methyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-2-methyl-, methyl ester, (2E)-(50704-04-6)
• EPA Substance Registry System: 2-Propenoic acid, 3-[4-(dimethylamino)phenyl]-2-methyl-, methyl ester, (2E)-(50704-04-6)

Safety Data

• Hazardous Substances Data: 50704-04-6(Hazardous Substances Data)

Upstream product

• 586-77-6 4-bromo-N,N-dimethylaniline 
• 80-62-6 methacrylic acid methyl ester 

Relevant articles and documents

Air-stable trialkylphosphonium salts: simple, practical, and versatile replacements for air-sensitive trialkylphosphines. Applications in stoichiometric and catalytic processes.

Trialkylphosphines furnish unusual, sometimes unique, reactivity in a range of transformations. Unfortunately, their utility is compromised by their sensitivity to oxidation. We have examined a simple but powerful strategy for addressing this problem: convert air-sensitive trialkylphosphines into air-stable phosphonium salts via protonation on phosphorus. These robust salts serve as direct replacements for the corresponding phosphines (simple deprotonation under the reaction conditions by a Bronsted base liberates the trialkylphosphine) in a diverse set of applications. [reaction: see text]

PROCESS FOR PRODUCING PHOSPHONIUM BORATE COMPOUND, NOVEL PHOSPHONIUM BORATE COMPOUND, AND METHOD OF USING THE SAME

The invention relates to a phosphonium borate compound represented by Formula (I) (hereinafter, the compound (I)). The invention has objects of providing (A) a novel process whereby the compound is produced safely on an industrial scale, by simple reaction operations and in a high yield; (B) a novel compound that is easily handled; and (C) novel use as catalyst. ????????Formula (I) : (R1)(R2)(R3)PH·BAr4?????(I) wherein R1, R2, R3 and Ar are as defined in the specification. The process (A) includes reacting a phosphine with a) HCl or b) H2SO4 to produce a) a hydrochloride or b) a sulfate; and reacting the salt with a tetraarylborate compound. The compound (B) has for example a secondary or tertiary alkyl group as R1 and is easily handled in air without special attention. The use (C) is characterized in that the compound (I) is used instead of an unstable phosphine compound of a transition metal complex catalyst for catalyzing C-C bond, C-N bond and C-O bond forming reactions and the compound produces an effect that is equal to that achieved by the transition metal complex catalyst.