510-39-4

Basic information

• Product Name: Maleoabietic anhydride
• Synonyms: 17,19-Dinoratis-15-ene-4,13,14-tricarboxylic acid,16-(1-methylethyl)-,cyclic 13,14-anhydride,(4R,8R,12R,13R,14R)-;Maleopimaric acid
• CAS NO: 510-39-4
• Molecular Formula: C₂₄H₃₂O₅
• Molecular Weight: 400.515
• Mol File: 510-39-4.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 565.9°Cat760mmHg
• Flash Point: 192.4°C
• Density: 1.24g/cm³
• CAS DataBase Reference: Maleoabietic anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: Maleoabietic anhydride(510-39-4)
• EPA Substance Registry System: Maleoabietic anhydride(510-39-4)

Safety Data

• Hazardous Substances Data: 510-39-4(Hazardous Substances Data)

Usage

General Description

Maleoabietic anhydride is a chemical compound derived from the rosin of pine trees. It is a bicyclic diterpenoid anhydride with potential anticancer and antitumor properties. Studies have shown that maleoabietic anhydride can inhibit the growth of various cancer cell lines, including breast and prostate cancer cells, by inducing apoptosis and disrupting the cell cycle. It has also been found to inhibit the activity of certain enzymes involved in cancer progression, making it a potential candidate for the development of new anticancer drugs. Additionally, maleoabietic anhydride has demonstrated anti-inflammatory and antioxidative properties, further highlighting its potential therapeutic benefits.

Upstream product

• 108-31-6 maleic anhydride 
• 514-10-3 abietic acid 
• 79-54-9 levopimaric acid 

Downstream Products

• 1254181-93-5 C₃₇H₄₂N₂O₄ 
• 1254181-95-7 C₃₈H₄₄N₂O₅ 
• 1254181-97-9 C₃₈H₄₄N₂O₆ 
• 1254181-98-0 C₃₉H₄₆N₂O₆ 
• 1254181-99-1 C₄₀H₄₆N₂O₇ 
• 1254182-00-7 C₄₁H₄₈N₂O₇ 
• 1254182-03-0 C₄₂H₅₀N₂O₇ 
• 1254182-05-2 C₄₂H₅₀N₂O₇ 
• 1254182-07-4 C₄₃H₅₂N₂O₇ 
• 1254182-09-6 C₄₃H₅₂N₂O₇ 
• 1254182-10-9 C₄₆H₅₈N₂O₇ 
• 1254182-11-0 C₄₈H₆₂N₂O₇ 
• 1254182-12-1 C₅₆H₇₈N₂O₇ 
• 1254182-13-2 C₄₂H₄₈N₂O₇ 

Relevant articles and documents

Two-dimensional INADEQUATE 13C NMR Studies of Maleopimaric Acid, the Diels-Alder Adduct of Levopimaric Acid and Maleic Anhydride, and of Abietic Acid

Two-dimensional INADEQUATE 13C NMR was used to establish firmly the carbon-carbon connectivities present in abietic acid and maleopimaric acid, i. e. the adduct of levopimaric acid and maleic anhydride.This information leads to unambiguous assignments for the 20 and 24 carbon resonances of abietic acid and maleopimaric acid, respectively.Proton-carbon chemical shift correlation and NOE experiments further revealed the three-dimensional structure of maleopimaric acid.

CO2-Responsive Pickering Emulsions Stabilized by a Bio-based Rigid Surfactant with Nanosilica

A novel CO2-responsive surfactant, maleopimaric acid glycidyl methacrylate ester 3-(dimethylamino)propylamine imide (MPAGN), based on sustainable resource of rosin was synthesized and used to prepare a kind of CO2-responsive Pickering emulsions with nanosilica. MPAGN can be reversibly responsive to CO2 and N2 between active cationic (MPAGNH+) and inactive nonionic (MPAGN), leading to adsorb on or desorb from the surface of nanosilica, then stabilize or break emulsion. CO2-responsive behavior of MPAGN was verified by cycle change of pH and conductivity with bubbling CO2 and N2 alternately. The type of adsorption of MPAGNH+ at the particle-water interface was explained according to the adsorption isotherms. The mechanisms of stabilization, destabilization, and restabilization of Pickering emulsion were analyzed according to zeta potentials and droplet size. This Pickering emulsion can be reversible between stable and unstable by bubbling CO2 and N2 alternately. Moreover, this emulsifier can be recycled when new oil was added after removing the initial oil. Therefore, it not only has economic benefits but also has an environmentally friendly property.

Rosin-based porous heterogeneous catalyst functionalized with hydroxyl groups and triazole groups for CO2 chemical conversion under atmospheric pressure condition

Development of efficient, green and recyclable heterogeneous catalysts for the chemical conversion of CO2 into cyclic carbonates with excellent yields under atmospheric pressure condition is still a very challenging task. Herein, a class of biomass-derived hyper-cross-linked porous heterogeneous catalysts MPAc-Br and MPAc-OH-Br, based on easily available and sustainable rosin, was synthesized by Friedel–Crafts polymerization and the further N-alkylation of triazole groups. Compared with MPAc-Br, the bifunctional catalyst MPAc-OH-Br (bearing triazole IL groups and -OH groups) exhibited higher catalytic activity for direct chemical conversion of CO2 into cyclic carbonates (up to 99% yields) under metal-, solvent-free and atmospheric pressure conditions. The rosin-based porous molecular structure and bifunctional groups on the surface of MPAc-OH-Br played a very important role in the promoting the cycloaddition of CO2 with epoxides under the optimal conditions. Furthermore, MPAc-OH-Br exhibited good stability and reusability (96% yield after 10 recycles).

Sodium alkylmaleimide carboxylate, and preparation method and application thereof

The invention discloses a sodium alkylmaleimide carboxylate, and a preparation method and an application thereof. The structural formula of the sodium alkylmaleimide carboxylate is shown in the description, and n in the formula is 8-16. The preparation method of the sodium alkylmaleimide carboxylate comprises the following steps: 1) performing a D-A addition reaction on rosin and maleic anhydrideto obtain maleated rosin; 2) performing an imidization reaction on the maleated rosin and alkylamine to obtain alkylmaleimide carboxylic acid; and 3) carrying out a neutralization reaction on the alkylmaleimide carboxylic acid and a sodium-containing basifying agent. The invention further discloses the application of the sodium alkylmaleimide carboxylate. The sodium alkylmaleimide carboxylate enriches the variety of rosin surfactant products, improves the added values of rosin, has mild preparation conditions, and has the advantages of safety, no toxicity, no pollution, greenness and environmental protection.