510730-17-3Relevant articles and documents
Stereoselective synthesis of (E)- and (Z)-3-hydroxy-2-methyl-1-alkenyl iodides by base-promoted ring-opening of iodomethylated epoxides
Ichige, Takahiro,Matsuda, Daisuke,Nakata, Masaya
, p. 4843 - 4848 (2006)
Both (E)- and (Z)-3-hydroxy-2-methyl-1-alkenyl iodides were stereoselectively synthesized from iodomethylated epoxides by treatment with sodium hexamethyldisilazane in DMF and with LDA in THF (or lithium 2,2,6,6-tetramethylpiperidide in THF), respectively
PROTEIN KINASE C AGONISTS
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Paragraph 0287, (2020/09/12)
The present disclosure relates generally to certain diacylglycerol lactone compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions dis
Conformationally constrained analogues of diacylglycerol. 24. Asymmetric synthesis of a chiral (R)-DAG-lactone template as a versatile precursor for highly functionalized DAG-lactones
Kang, Ji-Hye,Siddiqui, Maqbool A.,Sigano, Dina M.,Krajewski, Krzysztof,Lewin, Nancy E.,Pu, Yongmei,Blumberg, Peter M.,Lee, Jeewoo,Marquez, Victor E.
, p. 2413 - 2416 (2007/10/03)
(Equation Presented) Commercially available 2-methylenepropane-1,3-diol was converted to chiral epoxide (R)-2 via Sharpless asymmetric epoxidation in >96% ee. Regiospecific epoxide ring opening and reduction of the intermediate alkyne set the stage for a
