5117-17-9

Basic information

• Product Name: 1,1-diethyl-2-selenourea
• Synonyms: 1,1-diethyl-2-selenourea;1,1-Diethylselenourea;USAF B-100
• CAS NO: 5117-17-9
• Molecular Formula: C₅H₁₂N₂Se
• Molecular Weight: 179.12218
• EINECS: 225-855-9
• Mol File: 5117-17-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: 1,1-diethyl-2-selenourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-diethyl-2-selenourea(5117-17-9)
• EPA Substance Registry System: 1,1-diethyl-2-selenourea(5117-17-9)

Safety Data

• Hazardous Substances Data: 5117-17-9(Hazardous Substances Data)

Usage

Safety Profile

Poison by intraperitoneal route. See also SELENIUM COMPOUNDS. When heated to decomposition it emits very toxic fumes of NOx and Se.

InChI:InChI=1/C5H11N2Se/c1-3-7(4-2)5(6)8/h6H,3-4H2,1-2H3

Upstream product

• 617-83-4 Diethylcyanamide 

Downstream Products

• 154437-04-4 diethyl-(4-phenyl-selenazol-2-yl)-amine 
• 617-83-4 Diethylcyanamide 
• 1666-13-3 diphenyl diselenide 
• 86297-11-2 1,2-bis(3-methoxyphenyl) diselenide 
• 50499-87-1 di-(3,4-dimethoxyphenyl) diselenide 

Relevant articles and documents

Selenoureas and thioureas are effective superoxide radical scavengers in vitro

Oxygen radicals, such as superoxide radicals, embellishing DNA, protein, lipids, etc., and carrying out the obstacle of the function of a cell is known. It depends for the oxidant level in the living body on the balance of a generation system and an elimination system of oxygen radicals, and research which controls an oxidant level in the living body is briskly done by taking in the substance which eliminates an oxygen radical. We investigated scavenging effects of superoxide radicals by selenoureas and thioureas using a highly sensitive and quantitative chemiluminescence method. At 330 nM, five selenoureas and five thioureas scavenged fractions of superoxide radicals (O 2-) ranging from 8.4% to 87.6%. Among five N,N-unsubstituted selenoureas and N,N-unsubstituted thioureas 1-selenocarbamoylpiperidine and 1-thiocarbamoylpyrrolidine were the most effective scavengers. A possibility that selenoureas could use it as a new superoxide anion-scavenging substance from the result of this research became clear.

A Simple Route to N,N-Disubstituted Selenoureas from N,N-Disubstituted Cyanamides

N,N-Disubstituted selenoureas 4 can be obtained in satisfactory yields by addition of an acid to a mixture of freshly prepared sodium selenide and N,N-disubstituted cyanamides 5.

Preparation and characterisation of N,N-disubstituted 2-amino-selenazoles

As a result of checking suited methods for preparing N,N-disubstituted 2-amino-selenazoles 14 as a nearly unknown class of highly reactive selenazoles a simple route starting from N,N-disubstituted selenoureas 12 has been elaborated and used for the synthesis of a series of these compounds. The necessary selenium-containing starting compounds 12 are available from N,N-disubstituted cyanamides 18 and hydrogen selenide.