512822-27-4

Basic information

• Product Name: N-Boc-9-azabicyclo[3.3.1]nonan-3-one
• Synonyms: N-Boc-9-azabicyclo[3.3.1]nonan-3-one;3-Oxo-9-aza-bicyclo[3.3.1]nonane-9-carboxylic acid tert-butyl ester;tert-butyl 3-oxo-9-azabicyclo[3.3.1]nonane-9-carboxylate;9-Boc-3-oxo-9-azabicyclo[...;9-Boc-3-oxo-9-azabicyclo[3.3.1]nonane;9-Boc-9-aza-bicyclo[3.3.1]nonan-3-one
• CAS NO: 512822-27-4
• Molecular Formula: C₁₃H₂₁NO₃
• Molecular Weight: 239.31
• Product Categories: Amines and Anilines;Carbonyl Compounds
• Mol File: 512822-27-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 342.9 °C at 760 mmHg
• Flash Point: 161.2 °C
• Appearance: /
• Density: 1.1 g/cm³
• Vapor Pressure: 7.32E-05mmHg at 25°C
• Refractive Index: 1.5
• Storage Temp.: 2-8°C
• PKA: -1.65±0.20(Predicted)
• CAS DataBase Reference: N-Boc-9-azabicyclo[3.3.1]nonan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-9-azabicyclo[3.3.1]nonan-3-one(512822-27-4)
• EPA Substance Registry System: N-Boc-9-azabicyclo[3.3.1]nonan-3-one(512822-27-4)

Safety Data

• Hazardous Substances Data: 512822-27-4(Hazardous Substances Data)

Usage

General Description

N-Boc-9-azabicyclo[3.3.1]nonan-3-one is a type of organic compound belonging to the class of azabicyclo compounds. The use of this substance is predominantly in the field of organic synthesis. As a chemical reagent, it has significant importance in particular chemical reactions or processes. It's is part of a category of chemicals known as "Boc-amino acids and derivatives" that are characterized by the presence of a tert-butoxycarbonyl group (Boc) protecting an amine function. As with most chemicals, handling N-Boc-9-azabicyclo[3.3.1]nonan-3-one should be done with caution considering safety procedures to prevent potential harm.

InChI:InChI=1/C13H21NO3/c1-13(2,3)17-12(16)14-9-5-4-6-10(14)8-11(15)7-9/h9-10H,4-8H2,1-3H3

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 4390-39-0 9-azabicyclo[3.3.1]nonan-3-one 
• 72761-60-5 9-azabicyclo<3.3.1>nonan-3-one hydrochloride 
• 6164-62-1 9-methyl-9-azabicyclo[3.3.1]nonan-3-one hydrochloride 
• 552-70-5 pseudopelletierine 

Downstream Products

• 934180-37-7 tert-butyl (1R,3r,5S)-3-hydroxy-9-azabicyclo[3.3.1]nonane-9-carboxylate 
• 72761-60-5 9-azabicyclo<3.3.1>nonan-3-one hydrochloride 

Relevant articles and documents

NOVEL 9-AZA-BICYCLO[3.3.1]NON-3-YLOXY CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS

This invention relates to novel 9-aza-bicyclo[3.3.1]non-3-yloxy chromen-2-one derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

ANTI-INFLAMMATORY COMPOUNDS

The use of a steroid sulfatase inhibitor in the preparation of a medicament for the treatment of inflammatory diseases.

BICYCLIC FIVE-MEMBERED HETEROARYL DERIVATIVES AND THEIR USE AS RENIN INHIBITORS

The invention relates to novel five-membered heteroaryl derivatives and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions comprising one or more of those compounds and especially their use as inhibitors of renin.