51287-54-8 Usage
Description
1(3H)-Isobenzofuranone, 3-(phenylthio)-, also known as benzofuran-3-one-3-thiol, is a sulfur-containing heterocyclic compound with the molecular formula C12H8OS. It features a benzofuranone core with a phenylthio group attached at the 3-position, making it a versatile chemical with various industrial applications and potential biological activities.
Uses
Used in Pharmaceutical Industry:
1(3H)-Isobenzofuranone, 3-(phenylthio)is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs.
Used in Agrochemical Industry:
1(3H)-Isobenzofuranone, 3-(phenylthio)is also utilized as an intermediate in the synthesis of agrochemicals, playing a role in the creation of substances that can protect crops and enhance agricultural productivity.
Used in Organic Compounds Synthesis:
1(3H)-Isobenzofuranone, 3-(phenylthio)serves as an intermediate in the synthesis of other organic compounds, highlighting its importance in the broader field of organic chemistry.
Used in Antimicrobial Applications:
Due to its potential antimicrobial properties, 1(3H)-Isobenzofuranone, 3-(phenylthio)can be used as an antimicrobial agent, particularly in the development of new treatments for bacterial and fungal infections.
Used in Antioxidant Applications:
1(3H)-Isobenzofuranone, 3-(phenylthio)has been studied for its potential antioxidant properties, which could make it useful in the development of products that help prevent or mitigate oxidative stress and related conditions.
Used in Perfume Industry:
1(3H)-Isobenzofuranone, 3-(phenylthio)has been investigated for its potential use as a flavoring agent and fragrance ingredient in the perfume industry, capitalizing on its unique chemical structure to create novel scents.
Used in Flavor Industry:
Similarly, the compound's potential as a flavoring agent makes it a candidate for use in the development of new tastes and flavor profiles in the food and beverage industry.
Check Digit Verification of cas no
The CAS Registry Mumber 51287-54-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,2,8 and 7 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 51287-54:
(7*5)+(6*1)+(5*2)+(4*8)+(3*7)+(2*5)+(1*4)=118
118 % 10 = 8
So 51287-54-8 is a valid CAS Registry Number.
51287-54-8Relevant articles and documents
Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2?+?2?+?2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi
Wood, James M.,Satam, Nishikant S.,Almeida, Renata G.,Cristani, Vinicius S.,de Lima, Dênis P.,Dantas-Pereira, Luiza,Salom?o, Kelly,Menna-Barreto, Rubem F.S.,Namboothiri, Irishi N.N.,Bower, John F.,da Silva Júnior, Eufranio N.
, (2020/06/23)
Rhodium-catalyzed [2 + 2 + 2] cycloadditions, sulfonyl phthalide annulations and nitroalkene reactions have been employed for the synthesis of 56 quinone-based compounds. These were evaluated against Trypanosoma cruzi, the parasite that causes Chagas disease. The reactions described here are part of a program that aims to utilize modern, versatile and efficient synthetic methods for the one or two step preparation of trypanocidal compounds. We have identified 9 compounds with potent activity against the parasite; 3 of these were 30-fold more potent than benznidazole (Bz), a drug used for the treatment of Chagas disease. This article provides a comprehensive outline of reactions involving over 120 compounds aimed at the discovery of new quinone-based frameworks with activity against T. cruzi.
TiCl4-Mediated Preparation of Thiophthalide Derivatives via Formal Thio-Passerini Reactions
Ponra, Sudipta,Nyadanu, Aude,Ka?m, Laurent El,Grimaud, Laurence,Vitale, Maxime R.
supporting information, p. 4060 - 4063 (2016/08/30)
By the formal extension of the Passerini reaction to thiocarbonyl derivatives, the straightforward preparation of thiophthalides is disclosed. This method involves the intermediate formation of a sulfanyl-phthalide and a titanium tetrachloride mediated is
First synthesis of 9,10-dimethoxy-2-methyl-1,4-anthraquinone: A naturally occurring unusual anthraquinone
Mal, Dipakranjan,Ray, Sutapa
experimental part, p. 3014 - 3020 (2009/04/07)
The synthesis of 9,10-dimethoxy-2-methyl-1,4-anthraquinone, an unusual quinone, was achieved in five steps from p-benzoquinone. A Kochi-Anderson radical methylation features as the key step in the synthesis. The chemistry of a cyclopropa-1,4-anthracenedio