515160-77-7

Basic information

• Product Name: toluene-4-sulfonic acid 2-(5-amino-8-furan-2-yl-[1,2,4]triazolo[5,1-i]purin-3-yl)-ethyl ester
• CAS NO: 515160-77-7
• Molecular Weight: 439.454
• Mol File: 515160-77-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: toluene-4-sulfonic acid 2-(5-amino-8-furan-2-yl-[1,2,4]triazolo[5,1-i]purin-3-yl)-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: toluene-4-sulfonic acid 2-(5-amino-8-furan-2-yl-[1,2,4]triazolo[5,1-i]purin-3-yl)-ethyl ester(515160-77-7)
• EPA Substance Registry System: toluene-4-sulfonic acid 2-(5-amino-8-furan-2-yl-[1,2,4]triazolo[5,1-i]purin-3-yl)-ethyl ester(515160-77-7)

Safety Data

• Hazardous Substances Data: 515160-77-7(Hazardous Substances Data)

Upstream product

• 82499-03-4 2-amino-6-bromopurine 
• 3326-71-4 2-furoic acid hydrazide 

Relevant articles and documents

3H-[1,2,4]-Triazolo[5,1-i]purin-5-amine derivatives as adenosine A2A antagonists

A novel series of 3-substituted-8-aryl-[1,2,4]-triazolo[5,1-i]purin-5-amine analogs related to Sch 58261 was synthesized in order to identify potent adenosine A2A receptor antagonists with improved selectivity over the A1 receptor, physiochemical properties, and pharmacokinetic profiles as compared to those of Sch 58261. As a result of structural modifications, numerous analogs with excellent in vitro binding affinities and selectivities were identified. Moreover, compound 27 displayed both superior in vitro and highly promising in vivo profiles.