51533-70-1 Usage
Description
Diethyl (2-methylallyl)phosphonate 97 is an organophosphorous compound that plays a significant role in the synthesis of various organic compounds, including α-aminophosphonate derivatives and azaphosphones. It is known for its participation in the Horner-Wadsworth-Emmons reaction, which is crucial for forming conjugated carbon-carbon double bonds.
Uses
Used in Pharmaceutical Industry:
Diethyl (2-methylallyl)phosphonate 97 is used as a reagent for the Horner-Wadsworth-Emmons reaction, which is essential in the synthesis of α-aminophosphonate derivatives and azaphosphones. These derivatives exhibit analgesic and anti-inflammatory properties, making them valuable in the development of new pharmaceuticals for pain relief and inflammation management.
Used in Chemical Synthesis:
Diethyl (2-methylallyl)phosphonate 97 is used as a reactant in the enantioselective total synthesis of 10-isocyano-4-cadinene, an antifouling agent. This application highlights its importance in creating compounds that can help prevent the growth of marine organisms on ship hulls and other submerged structures.
Used in Organic Chemistry Research:
In the field of organic chemistry, Diethyl (2-methylallyl)phosphonate 97 is used for the regiospecific preparation of 4-oxo-2-alkenylphosphonates (OAP) through silylation followed by Friedel-Crafts acylation and isomerization. OAP serves as building blocks for the construction of polyethylenic chains, which are essential in various chemical reactions and the synthesis of complex organic molecules.
Used in the Synthesis of Azaphosphone:
Diethyl (2-methylallyl)phosphonate 97 is also utilized in the synthesis of azaphosphone, a potent analgesic and anti-inflammatory agent. This application demonstrates its versatility in contributing to the development of new and effective pain relief and anti-inflammatory medications.
Check Digit Verification of cas no
The CAS Registry Mumber 51533-70-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,5,3 and 3 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 51533-70:
(7*5)+(6*1)+(5*5)+(4*3)+(3*3)+(2*7)+(1*0)=101
101 % 10 = 1
So 51533-70-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H17O3P/c1-5-10-12(9,11-6-2)7-8(3)4/h3,5-7H2,1-2,4H3
51533-70-1Relevant articles and documents
Palladium-catalyzed preparation of dialkyl allylphosphonates. A new preparation of diethyl 2-oxoethylphosphonate
Malet,Moreno-Manas,Pleixats
, p. 2219 - 2228 (2007/10/02)
Palladium-catalyzed Michaelis-Arbuzov reaction of allyl acetates with trialkyl phosphites affords dialkyl allylphosphonates. Diethyl 2-oxoethylphosphonate is efficiently prepared by ozonization of diethyl allylphosphonate.
