51558-95-3Relevant articles and documents
Catalytic and Atom-Economic Intermolecular Amidoselenenylation of Alkenes
Tang,Wang, Weilin,Zhao, Yinjiao,Zhang, Meng,Dai, Xin
, p. 176 - 179 (2016)
A method for the simple, efficient, and atom-economic amidoselenenylation of simple alkenes under mild conditions using TiCl4 as a catalyst and N-(phenylseleno)phthalimide as both a nitrogen and selenium source was developed. A broad range of olefins can be applied to afford vicinal amidoselenides in good yield and with high regioselectivity and diastereoselectivity.
Visible-light-induced oxidative coupling of vinylarenes with diselenides leading to α-aryl and α-alkyl selenomethyl ketones
Liu, Gong-Qing,Yi, Wei,Wang, Peng-Fei,Liu, Ji,Ma, Meng,Hao, Da-Yun,Ming, Liang,Ling, Yong
supporting information, p. 1840 - 1846 (2021/03/09)
A visible-light-induced oxidative coupling of diselenides with readily available vinylarenes is demonstrated. This benign protocol allows one to access a wide range of α-aryl and α-alkyl selenomethyl ketones in good yields with excellent functional group compatibility. The distinct advantages of this protocol over all previous methods include the use of a green solvent and air as an oxidant and the lack of a photocatalyst, a base, and an oxidant as well as better green chemistry matrices. Furthermore, the title reaction can be performed with natural sunlight, the most sustainable energy source imaginable. Additionally, the mild reaction conditions, easy operation and suitability for the modification of styrene-functionalized biomolecules make the current reaction system a more attractive method for the synthesis of a variety of medicinal and agrochemical compounds of interest.
Method for promoting synthesis of beta-hydroxyl selenide compound by visible light
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Paragraph 0046-0049, (2021/05/01)
The invention relates to the technical field of organic synthetic chemistry, in particular to a method for promoting synthesis of a beta-hydroxyl selenide compound by visible light. The method comprises the following steps: A, sequentially adding a compound 1 and a compound 2 into a reactor; B, stirring the compound 1 and the compound 2 for reaction at a certain temperature under the irradiation of a light source under an open condition; C, after the reaction is finished, evaporating the solvent under reduced pressure to obtain a crude product; and D, carrying out column chromatography purification to obtain the beta-hydroxy selenide compound 3. According to the method, olefin and diselenide are used as raw materials, one of an acetonitrile/water mixed solvent and an acetone/water mixed solvent is used as a solvent, the reaction temperature is room temperature, and the beta-hydroxyl selenide compound is efficiently synthesized under the irradiation of a white fluorescent light source; compared with the traditional synthesis method, the method has the advantages that the reaction conditions are mild and can be smoothly carried out at room temperature; operation is simple, and all operations can be carried out in an open system; and raw materials are easy to obtain, the yield is high, functional group compatibility is good, and the substrate application range is wide.
Automated Electrochemical Selenenylations
Amri, Nasser,Wirth, Thomas
supporting information, p. 1751 - 1761 (2020/06/08)
Integrated electrochemical reactors in automated flow systems were utilised for selenenylation reactions. The automation allowed multiple electrochemical reactions of a programmed sequence to be performed in a fully autonomous way. Many functionalised selenenylated products were synthesised in short reaction times in good to high yields.
