51744-98-0

Basic information

• Product Name: [2.2]Metacyclophan
• CAS NO: 51744-98-0
• Molecular Weight: 208.303
• Mol File: 51744-98-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [2.2]Metacyclophan(CAS DataBase Reference)
• NIST Chemistry Reference: [2.2]Metacyclophan(51744-98-0)
• EPA Substance Registry System: [2.2]Metacyclophan(51744-98-0)

Safety Data

• Hazardous Substances Data: 51744-98-0(Hazardous Substances Data)

Upstream product

• 626-15-3 1,3-bis-(bromomethyl)benzene 
• 605-39-0 2,2'-dimethyl-1,1'-biphenyl 
• 89032-34-8 4-(2-oxo-2-phenylethyl)-2,6-dimethylenebicyclo<3.1.0>hexane 
• 626-16-4 3-(chloromethyl)benzyl chloride 

Downstream Products

• 129-00-0 pyrene 
• 6628-98-4 4,5-dihydropyrene 
• 781-17-9 4,5,9,10-tetrahydropyrene 
• 55775-16-1 1,2,3,3a,4,5,9,10-octahydropyrene 
• 5385-37-5 1,2,3,3a,4,5-hexahydropyrene 
• 53076-44-1 1,2,3,3a,4,5,9,10,10a,10b-decahydropyrene 
• 10549-27-6 2-bromo-4,5,9,10-tetrahydropyrene 
• 100-42-5 styrene 
• 106-42-3 para-xylene 
• 694-87-1 benzocyclobutene 
• 108-38-3 m-xylene 
• 108-88-3 toluene 
• 71-43-2 benzene 
• 1732-13-4 1,2,3,6,7,8-hexahydropyrene 

Relevant articles and documents

A simple synthetic method of cyclophanes by Lanthanoid-mediated coupling of bis(bromomethyl)benzenes

The coupling of bis(bromomethyl)benzenes with iodized samarium, cerium or misch metal gives cyclophanes in satisfactory yields in a short time.

Preperations and Reactions of Symmetrical Dimethylenebiphenyl Dianions; Conformations of -o-Cyclophanes. A Simple NMR method for Determining Twist Angles in Biphenyls

With n-butyllithium / potassium tert-butoxide, a proton is removed from each methyl group of the symmetrical dimethylbiphenyls to give dianions in good yield.The reactions of these dianions with alkyl halides, dialkyl sulfates, trimethylchlorosilane, trimethylchlorogermane, α,ω-dihalides, and oxidizing agents were found to provide the best routes to many symmetrically substituted biphenyls, including - and cyclophanes.NMR and molecular mechanical studies of some of these cyclophanes gave information on their preferred conformations.An NMR method for determining the angle of twist in biphenyls from the chemical shifts of the ortho hydrogens is developed.