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51828-70-7

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51828-70-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 51828-70-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,8,2 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 51828-70:
(7*5)+(6*1)+(5*8)+(4*2)+(3*8)+(2*7)+(1*0)=127
127 % 10 = 7
So 51828-70-7 is a valid CAS Registry Number.

51828-70-7Relevant articles and documents

HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA

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Paragraph 0185; 0186, (2013/11/05)

The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds

Ethacrynic acid as a lead structure for the development of potent urease inhibitors

Janser, Ingo,Vortolomei, Caitlyn M.,Meka, Ranjith K.,Walsh, Courtney A.,Janser, Romy F.J.

, p. 660 - 664 (2013/08/15)

Ethacrynic acid and a series of its analogues were synthesized and subsequently evaluated for their inhibitory effect on jack bean urease. Ethacrynic acid showed, even at low concentrations, very potent inhibitory activity against the enzyme. For ethacrynic acid, the inhibition potential increased with increasing preincubation time of ethacrynic acid and enzyme, whereas for some other compounds a higher preincubation time lead to a significant reduction of their activity. We could demonstrate that the α,β-unsaturated carbonyl unit of our compounds is mandatory to inhibit the enzyme, possibly due to its ability to bind to cysteine residues in the active site of the jack bean urease.

CHEMICAL COMPOUNDS

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Page/Page column 40-41, (2008/06/13)

The present invention discloses novel compounds with a variety of therapeutic uses. More particularly, the invention discloses novel symmetrical triphenyl compounds that are particularly useful for selective estrogen receptor modulation.

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