519032-00-9

Basic information

• Product Name: methyl 5-(benzoyloxy)-2-[4-(tert-butoxycarbonyl)-2-methylpiperazin-2-yl]-6-hydroxypyrimidine-4-carboxylate
• Synonyms: methyl 5-(benzoyloxy)-2-[4-(tert-butoxycarbonyl)-2-methylpiperazin-2-yl]-6-hydroxypyrimidine-4-carboxylate
• CAS NO: 519032-00-9
• Molecular Weight: 472.498
• Mol File: 519032-00-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 5-(benzoyloxy)-2-[4-(tert-butoxycarbonyl)-2-methylpiperazin-2-yl]-6-hydroxypyrimidine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-(benzoyloxy)-2-[4-(tert-butoxycarbonyl)-2-methylpiperazin-2-yl]-6-hydroxypyrimidine-4-carboxylate(519032-00-9)
• EPA Substance Registry System: methyl 5-(benzoyloxy)-2-[4-(tert-butoxycarbonyl)-2-methylpiperazin-2-yl]-6-hydroxypyrimidine-4-carboxylate(519032-00-9)

Safety Data

• Hazardous Substances Data: 519032-00-9(Hazardous Substances Data)

Upstream product

• 126937-41-5 1-(benzyloxycarbonyl)-4-(tert-butoxycarbonyl)-2-piperazinecarboxylic acid 
• 519031-99-3 2-[N-(1,2-bis-methoxycarbonyl-vinyloxy)-carbamimidoyl]-2-methyl-piperazine-1,4-dicarboxylic acid 1-benzyl ester 4-tert-butyl ester 
• 940868-30-4 1-benzyl 4-tert-butyl 2-[amino(hydroxyimino)methyl]-2-methylpiperazine-1,4-dicarboxylate 
• 940868-18-8 1-[(benzyloxy)carbonyl]-4-(tert-butoxycarbonyl)-2-methylpiperazine-2-carboxylic acid 
• 518048-20-9 1-benzyl-4-tert-butyl-2-cyano-2-methylpiperazine-1,4-dicarboxylate 
• 518048-21-0 1-benzyl 4-tert-butyl 2-[5-(benzoyloxy)-4-hydroxy-6-(methoxycarbonyl)pyrimidin-2-yl]-2-methylpiperazine-1,4-dicarboxylate 

Downstream Products

• 519032-02-1 tert-butyl 3-(4-{[(4-fluorobenzyl)amino]carbonyl}-5,6-dihydroxypyrimidin-2-yl)-3,4-dimethylpiperazine-1-carboxylate 
• 519032-03-2 2-(1,2-dimethylpiperazin-2-yl)-N-(4-fluorobenzyl)-5,6-dihydroxypyrimidine-4-carboxamide 

Relevant articles and documents

Dihydroxy-pyrimidine and N-methylpyrimidone HIV-integrase inhibitors: Improving cell based activity by the quaternarization of a chiral center

In the context of HIV-integrase, dihydroxypyrimidine and N-methyl pyrimidone inhibitors the cellular activity of this class of compounds has been optimized by the introduction of a simple methyl substituent in the α-position of the C-2 side chains. Enhanc