51939-71-0 Usage
Description
CHROMANE-2-CARBOXYLIC ACID is an organic compound that serves as a key building block in the synthesis of various pharmaceutical compounds. It is characterized by its unique chemical structure, which includes a chromane ring and a carboxylic acid functional group. This structure allows it to be utilized in the development of a range of therapeutic agents.
Uses
Used in Pharmaceutical Industry:
CHROMANE-2-CARBOXYLIC ACID is used as a key intermediate in the synthesis of 4-quinazolinones, which are Rho kinase inhibitors. These inhibitors have potential applications in the treatment of glaucoma, hypertension, and spinal cord injuries. CHROMANE-2-CARBOXYLIC ACID's ability to inhibit Rho kinase activity makes it a valuable asset in the development of these therapeutic agents.
Used in Antibacterial Applications:
CHROMANE-2-CARBOXYLIC ACID is also used in the preparation of chromanyl-benzamidazoles, which are anti-bacterial compounds. These compounds have the potential to combat bacterial infections by targeting specific bacterial processes or structures. The versatility of CHROMANE-2-CARBOXYLIC ACID in the synthesis of various pharmaceutical compounds highlights its importance in the development of new treatments for a range of medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 51939-71-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,9,3 and 9 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 51939-71:
(7*5)+(6*1)+(5*9)+(4*3)+(3*9)+(2*7)+(1*1)=140
140 % 10 = 0
So 51939-71-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H10O3/c11-10(12)9-6-5-7-3-1-2-4-8(7)13-9/h1-4,9H,5-6H2,(H,11,12)
51939-71-0Relevant articles and documents
Model Reactions for the Enantioselective Synthesis of γ-Rubromycin: Stereospecific Intramolecular Photoredox Cyclization of an ortho-Quinone Ether to a Spiroacetal
Wakita, Fumihiro,Ando, Yoshio,Ohmori, Ken,Suzuki, Keisuke
supporting information, p. 3928 - 3932 (2018/07/25)
A model study for the enantioselective total synthesis of γ-rubromycin has revealed a promising approach for constructing the chiral, nonracemic bicyclic spiroacetal via the stereospecific photoredox reaction of 1,2-naphthoquinone ether.
