51982-45-7

Basic information

• Product Name: cholesta-5,7,9-trien-3 beta-ol
• Synonyms: cholesta-5,7,9-trien-3 beta-ol;Cholesta-5,7,9(11)-trien-3β-ol
• CAS NO: 51982-45-7
• Molecular Formula: C₂₇H₄₂O
• Molecular Weight: 382.62
• Mol File: 51982-45-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 513.3°Cat760mmHg
• Flash Point: 217.2°C
• Appearance: /
• Density: 1.01g/cm³
• Vapor Pressure: 1.1E-12mmHg at 25°C
• Refractive Index: 1.546
• PKA: 14.88±0.70(Predicted)
• CAS DataBase Reference: cholesta-5,7,9-trien-3 beta-ol(CAS DataBase Reference)
• NIST Chemistry Reference: cholesta-5,7,9-trien-3 beta-ol(51982-45-7)
• EPA Substance Registry System: cholesta-5,7,9-trien-3 beta-ol(51982-45-7)

Safety Data

• Hazardous Substances Data: 51982-45-7(Hazardous Substances Data)

Usage

Uses

Cholesta-5,7,9-trien-3β-ol is a steroid analogs to mimic natural cholesterol.

InChI:InChI=1/C27H42O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,14,18-19,21,23-24,28H,6-8,11-13,15-17H2,1-5H3/t19-,21+,23-,24+,26+,27-/m1/s1

Upstream product

• 434-16-2 7-dehydrocholesterol 
• 24637-52-3 5α-cholestadiene-(7,9(11))-diol-(3β,6β) 
• 108-24-7 acetic anhydride 
• 24637-52-3 5α-cholestadiene-(7,9(11))-diol-(3β,6α) 
• 67-66-3 chloroform 
• 1600-27-7 mercury(II) diacetate 
• 64-19-7 acetic acid 
• 1255-91-0 Δ^5,7,9-cholestatrien-3β-ol acetate 
• 1059-86-5 7-Dehydrocholesteryl acetate 

Downstream Products

• 1255-91-0 Δ^5,7,9-cholestatrien-3β-ol acetate 
• 102582-50-3 3β-benzoyloxy-cholesta-5,7,9(11)-triene 
• 85135-02-0 Δ^5,7,9-cholestatriene 3β-O-phosphate 
• 78342-39-9 5,8α-Epidioxy-5α-cholesta-6,9(11)-dien-3β-ol 

Relevant articles and documents

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Cyclodextrin-catalyzed extraction of fluorescent sterols from monolayer membranes and small unilamellar vesicles

This study examined the kinetics of sterol desorption from monolayer and small unilamellar vesicle membranes to 2-hydroxypropyl-β-cyclodextrin. The sterols used include cholesterol, dehydroergosterol (ergosta-5,7,9,(11),22- tetraen-3β-ol) and cholestatrienol (cholesta-5,7,9,(11)-trien-3β-ol). Desorption rates of dehydroergosterol and cholestatrienol from pure sterol monolayers were faster (3.3-4.6-fold) than the rate measured for cholesterol. In mixed monolayers (sterol: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine 30:70 mol%), both dehydroergosterol and cholestatrienol desorbed faster than cholesterol, clearly indicating a difference in interfacial behavior of these sterols. In vesicle membranes desorption of dehydroergosterol was slower than desorption of cholestatrienol, and both rates were markedly affected by the phospholipid composition. Desorption of sterols was slower from sphingomyelin as compared to phosphatidylcholine vesicles. Desorption of fluorescent sterols was also faster from vesicles prepared by ethanol-injection as compared to extruded vesicles. The results of this study suggest that dehydroergosterol and cholestatrienol differ from cholesterol in their membrane behavior, therefore care should be exercised when experimental data derived with these probes are interpreted. (C) 2000 Elsevier Science Ireland Ltd.