52-85-7

Basic information

• Product Name: FAMPHUR
• Synonyms: BO-ANA;FAMOPHOS;FAMOPHOS(R);FAMPHUR;O,O-DIMETHYL-O-P-(DIMETHYLSULFAMOYL)PHENYL PHOSPHOROTHIOATE;WARBEXOL;WARBEX(R);AC 38023
• CAS NO: 52-85-7
• Molecular Formula: C₁₀H₁₆NO₅PS₂
• Molecular Weight: 325.34
• EINECS: 200-154-0
• Mol File: 52-85-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 53℃
• Boiling Point: 394.2 ºC at 760 mmHg
• Flash Point: >100 °C
• Appearance: /Liquid
• Density: 1.354 g/cm₃
• Vapor Pressure: 2.01E-06mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: APPROX 4°C
• PKA: -5.18±0.70(Predicted)
• Water Solubility: 5000 (est. 20 °C)
• Merck: 13,3963
• BRN: 2224254
• CAS DataBase Reference: FAMPHUR(CAS DataBase Reference)
• NIST Chemistry Reference: FAMPHUR(52-85-7)
• EPA Substance Registry System: FAMPHUR(52-85-7)

Safety Data

• Hazard Codes: T,Xn,F
• Statements: 24/25-36/38-63-43-36/37/38-23/24/25-45-67-40-39/23/24/25-11
• Safety Statements: 22-24/25-45-36/37-23-53-16-7
• RIDADR: 2783
• WGK Germany: 3
• RTECS: TF7650000
• HazardClass: 6.1(a)
• PackingGroup: II
• Hazardous Substances Data: 52-85-7(Hazardous Substances Data)

Usage

Description

FAMPHUR, also known as O,O-dimethyl-O-(3-methyl-4-nitrophenyl)thiophosphate, is a crystalline powder that is classified as very toxic. It functions as a cholinesterase inhibitor and is primarily used as an insecticide. Due to its toxicity, its use is restricted.

Uses

Used in Agricultural Industry:
FAMPHUR is used as an insecticide for controlling various pests in the agricultural industry. Its cholinesterase inhibiting properties make it effective in eliminating insects that can damage crops and reduce agricultural productivity.
Used in Chemical Industry:
FAMPHUR is used as a chemical intermediate in the synthesis of other compounds in the chemical industry. Its unique chemical structure allows it to be a valuable building block for creating various products.
Please note that the provided materials do not mention any uses of glycerol. The example given for Gallotannin is for illustrative purposes only and does not apply to FAMPHUR.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Organothiophosphates, such as FAMPHUR, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Metabolism

The principal degradation routes in mammals are P?Ophenyl bond cleavage and O-demethylation. Oxidative desulfuration and N-demethylation also take place to form toxic metabolites.

Toxicity evaluation

The acute oral LD50 for rats is 35–62 mg/kg.

InChI:InChI=1/C10H16NO5PS2/c1-11(2)19(12,13)10-7-5-9(6-8-10)16-17(18,14-3)15-4/h5-8H,1-4H3

Relevant articles and documents

Liquid formulations

A pour-on formulation comprising one or more ectoparasiticides in a solvent system comprising 80 to 98% w/v of a fixed oil and 2 to 20% w/v of a volatile silicone, a method for its preparations and its use in the control of ectoparasiticides on animals.