52059-50-4

Basic information

• Product Name: 3-(2-Bromoethyl)phenol
• Synonyms: 3-(2-Bromoethyl)phenol
• CAS NO: 52059-50-4
• Molecular Formula: C₈H₉BrO
• Molecular Weight: 201.06
• Mol File: 52059-50-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(2-Bromoethyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Bromoethyl)phenol(52059-50-4)
• EPA Substance Registry System: 3-(2-Bromoethyl)phenol(52059-50-4)

Safety Data

• Hazardous Substances Data: 52059-50-4(Hazardous Substances Data)

Usage

Description

3-(2-Bromoethyl)phenol is a chemical compound with the molecular formula C8H9BrO. It is an aromatic compound containing a benzene ring with a hydroxyl group and a 2-bromoethyl group attached. This chemical is commonly used as a building block in organic synthesis and can be utilized in the production of various pharmaceuticals, agrochemicals, and other fine chemicals. 3-(2-Bromoethyl)phenol is also used as a precursor in the synthesis of various biologically active compounds and has potential applications in the field of medicinal chemistry. Due to its versatile reactivity and functional groups, this chemical is of interest for the development of new molecules with potential pharmaceutical or biological activity.

Uses

Used in Pharmaceutical Industry:
3-(2-Bromoethyl)phenol is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
3-(2-Bromoethyl)phenol is used as a precursor in the production of agrochemicals, aiding in the creation of effective compounds for agricultural use.
Used in Fine Chemicals Industry:
3-(2-Bromoethyl)phenol is utilized in the synthesis of fine chemicals, which are essential for various industrial applications.
Used in Medicinal Chemistry:
3-(2-Bromoethyl)phenol is used as a precursor in the synthesis of biologically active compounds, playing a role in the advancement of medicinal chemistry and the discovery of new therapeutic agents.

Upstream product

• 13398-94-2 2-(3-hydroxyphenyl)ethanol 
• 5020-41-7 2-(3-methoxyphenyl)-ethanol 
• 1798-09-0 m-methoxyphenylacetic acid 
• 621-37-4 m-hydroxyphenylacetic acid 
• 2146-61-4 3-methoxyphenethyl bromide 

Downstream Products

• 111211-17-7 1-(3-hydroxy-phenethyl)-4-phenyl-piperidine-4-carboxylic acid ethyl ester 
• 113493-52-0 {2-[3-(2-Bromo-ethyl)-phenoxymethoxy]-ethyl}-trimethyl-silane 
• 140468-03-7 3-(2-bromoethyl)phenyl phosphorodichloridate 
• 40769-13-9 3-(2-Bromethyl)-phenyloxytrimethylsilan 
• 293756-89-5 2,4,6-tribromo-3-(2-bromoethyl)phenol 
• 51674-33-0 2-(3-Hydroxyphenyl)-methylaminoethane 
• 293756-90-8 2,4,6-tribromo-3-(2-bromoethyl)anisole 
• 293756-94-2 N-methyl-N-[2-(2,4,6-tribromo-3-hydroxy-phenyl)-ethyl]-formamide 
• 294210-58-5 lutamide C 
• 140466-61-1 Phosphoric acid 3-(2-bromo-ethyl)-phenyl ester 2-methoxy-3-tetradecyloxy-phenyl ester 
• 28749-99-7 5-(3-hydroxyphenyl)pentene 
• 52130-16-2 5-(m-Trimethylsilyloxyphenyl)-penten-1 
• 637358-90-8 1-(2-bromoethyl)-3-tert-butoxybenzene 
• 104126-76-3 3-(2-(pyrrolidin-1-yl)ethyl)phenol 

Relevant articles and documents

Non-nucleoside inhibitors of human adenosine kinase: Synthesis, molecular modeling, and biological studies

Adenosine kinase (AK) catalyzes the phosphorylation of adenosine (Ado) to AMP by means of a kinetic mechanism in which the two substrates Ado and ATP bind the enzyme in a binary and/or ternary complex, with distinct protein conformations. Most of the desc

Synthesis and biological activities of the marine bryozoan alkaloids convolutamines A, C and F, and lutamides A and C

Synthesis of convolutamines and lutamides, new 2,4,6-tribromo-3-methoxyphenethylamine alkaloids isolated from Floridian marine bryozoan Amathia convoluta, was accomplished by a sequence of reactions starting from 3-hydroxyphenethylamines. Cytotoxities of the synthetic lutamides, convolutamines and their de-O-methyl derivatives were examined using drug-sensitive and -resistant P388 as well as KB cell lines. The bioassay suggests that the 2,4,6-tribromo-3-methoxyphenethylamine is an indispensable unit for detection of the activities. Additionally, a reversal of drug resistance by those alkaloids is recognized. Copyright (C) 2000 Elsevier Science Ltd.

INTRAMOLECULAR RADICAL COUPLING OF A PHENOLIC ENOLATE: OXIDATIVE FRAGMENTATION OF THE SPIRODIKETONE INTERMEDIATE

Ferricyanide oxidation of the dianion of the phenolic β-diketone 6b in basic conditions effects intramolecular radical coupling to form the spirocyclic diketone 7 which leads to the hydroxy tetralone 8 via an oxidative fragmentation process.