521-62-0 Usage
Description
FRANGULIN A is a novel emodin rhamnoside derivative, which is supplied with certified chromatographic purity. It is produced by PhytoLab GmbH & Co. KG and has demonstrated anti-proliferative activities on various cancer cell lines in vitro.
Uses
Used in Anticancer Applications:
FRANGULIN A is used as an anticancer agent for its anti-proliferative activities on cancer cell lines. It has shown potential in inhibiting the growth and proliferation of cancer cells in vitro, making it a promising candidate for further research and development in the field of oncology.
Used in Pharmaceutical Industry:
FRANGULIN A is used as a pharmaceutical candidate for its potential applications in cancer treatment. Its anti-proliferative properties on cancer cell lines make it a valuable compound for the development of new drugs and therapies targeting various types of cancer.
Used in Research and Development:
FRANGULIN A is used as a research compound for the study of its anti-proliferative effects on cancer cells. It can be utilized in various experimental setups to better understand its mechanism of action and to explore its potential synergistic effects when combined with other chemotherapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 521-62-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 1 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 521-62:
(5*5)+(4*2)+(3*1)+(2*6)+(1*2)=50
50 % 10 = 0
So 521-62-0 is a valid CAS Registry Number.
InChI:InChI=1/C21H20O9/c1-7-3-10-14(12(22)4-7)18(26)15-11(17(10)25)5-9(6-13(15)23)30-21-20(28)19(27)16(24)8(2)29-21/h3-6,8,16,19-24,27-28H,1-2H3/t8-,16-,19+,20+,21-/m0/s1
521-62-0Relevant articles and documents
Synthesis and biological evaluation of cytotoxic activity of novel anthracene l-rhamnopyranosides
Song, Gaopeng,Liu, Hongchun,Zhang, Wei,Geng, Meiyu,Li, Yingxia
experimental part, p. 5183 - 5193 (2010/09/18)
A series of anthracene l-rhamnopyranosides were designed and synthesized in a practical way and their cytotoxic activity was examined in vitro. Most compounds exhibited both potent cytotoxicity against several tumor cell lines and high DNA binding capacity. The preliminary results showed that subtle modifications of rhamnosyl moiety in anthracene rhamnosides with acetyl group had a selective toxicity for different tumor cells and the displacement of C-10 carbonyl group in emodin by acetylmethylene group was helpful to improve the inhibitory activity. Lipophilicity of the anthracene glycosides was not a crucial factor for cytotoxicity and most molecules with good cytotoxicity could inhibit the catalytic activity of Top2α.