52107-93-4

Basic information

• Product Name: 2-iodo-3-methylbenzoyl chloride
• Synonyms: 2-iodo-3-methylbenzoyl chloride
• CAS NO: 52107-93-4
• Molecular Weight: 280.493
• Mol File: 52107-93-4.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: 2-iodo-3-methylbenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-iodo-3-methylbenzoyl chloride(52107-93-4)
• EPA Substance Registry System: 2-iodo-3-methylbenzoyl chloride(52107-93-4)

Safety Data

• Hazardous Substances Data: 52107-93-4(Hazardous Substances Data)

Upstream product

• 1885-77-4 3-methyl-2-nitrobenzonitrile 
• 4389-45-1 3-methylantranilic acid 
• 60310-07-8 3-Methyl-2-nitrobenzenecarboxamide 
• 108078-14-4 2-iodo-3-methylbenzoic acid 

Downstream Products

• 52107-79-6 1-(2-iodo-3-methylphenyl)ethanone 
• 1616629-18-5 3-benzyl-8-methyl-2-(4-oxopentyl)quinazolin-4(3H)-one 
• 1437798-34-9 3-benzyl-8-methyl-2-phenylquinazolin-4(3H)-one 
• 1581735-36-5 2-iodo-N-isopropyl-N,5-dimethylbenzamide 
• 1581735-35-4 2-iodo-N-isopropyl-N,3-dimethylbenzamide 
• 1243249-29-7 2-iodo-N,N-diisopropyl-3-methylbenzamide 
• 1559062-32-6 N-(3-hydroxypropyl)-2-iodo-3-methylbenzamide 
• 1559062-29-1 2-iodo-N-((1S)-(6-methoxyquinolin-4-yl)((2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)-3-methylbenzamide 
• 1415764-17-8 N-((1S,2S,5R)-1-(hydroxymethyl)-2-isopropyl-5-methylcyclohexyl)-2-iodo-3-methylbenzamide 
• 1374579-23-3 N-((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)-2-iodo-3-methylbenzamide 
• 1415764-15-6 C₁₇H₁₆INO₂ 
• 1415764-11-2 (S)-N-(2-hydroxy-2,4-dimethylpentan-3-yl)-2-iodo-3-methylbenzamide 
• 1415764-19-0 (S)-N-(2-cyclohexyl-2-hydroxyethyl)-2-iodo-3-methylbenzamide 

Relevant articles and documents

Palladium-Catalyzed Asymmetric Intramolecular Dearomative Heck Annulation of Aryl Halides to Furnish Indolines

An unprecedented Pd-catalyzed asymmetric intramolecular cascade cyclization of aryl halides with readily available arylboronic acids proceeds through a Heck-type dearomative cyclization terminated with arylation in the presence of Pd2(dba)3 (10 mol %), Cu

Synthesis of Spiro[benzofuran-2,2'-benzo[b]thiophene]-3,3'-diones via PIDA/CuBr-Mediated Spirocyclization

A phenyliodine(III) diacetate (PIDA)/CuBr-mediated construction of the novel 3H,3'H-spiro[benzofuran-2,2'-benzo[b]thiophene]-3,3'-dione skeleton was realized from the reaction of (Z)-3-hydroxy-1-(2-hydroxyphenyl)-3-(2-halogenphenyl)prop-2-en-1-ones with p

Copper-Catalyzed C(sp3)-S Bond and C(sp2)-S Bond Cross-Coupling of 2-(2-Iodobenzoyl) Substituted or 2-(2-Iodobenzyl) Substituted 1,2,3,4-Tetrahydroisoquinolines with Potassium Sulfide: Synthesis of Isoquinoline-Fused 1,3-Benzothiazine Scaffolds

The sulfuration reaction of 2-(2-iodobenzoyl) substituted, or 2-(2-iodobenzyl) substituted 1,2,3,4-tetrahydroisoquinolines with potassium sulfide proceeded in the presence of copper catalysts to give tetrahydroisoquinoline-fused 1,3-benzothiazine scaffolds in moderate to appropriate yields. This protocol provided an efficient and simple strategy to construct the corresponding benzothiazine derivatives via formation of C(sp3)-S bond and C(sp2)-S bond, which the C-S bonds formed via different routes in this reaction (traditional cross-coupling reaction via the cleavage of C-I bond and oxidative cross-coupling reaction via C(sp3)-H bond functionalization).