52121-06-9

Basic information

• Product Name: 2-[(2Z)-2-[(ethylcarbamoyl)imino]-5-nitro-1,3-thiazol-3(2H)-yl]-N,N-dipropylacetamide
• CAS NO: 52121-06-9
• Molecular Formula: C₁₄H₂₃N₅O₄S
• Molecular Weight: 357.4285
• Mol File: 52121-06-9.mol
• Article Data: 1

Chemical Properties

• Density: 1.31g/cm³
• Refractive Index: 1.599
• CAS DataBase Reference: 2-[(2Z)-2-[(ethylcarbamoyl)imino]-5-nitro-1,3-thiazol-3(2H)-yl]-N,N-dipropylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2Z)-2-[(ethylcarbamoyl)imino]-5-nitro-1,3-thiazol-3(2H)-yl]-N,N-dipropylacetamide(52121-06-9)
• EPA Substance Registry System: 2-[(2Z)-2-[(ethylcarbamoyl)imino]-5-nitro-1,3-thiazol-3(2H)-yl]-N,N-dipropylacetamide(52121-06-9)

Safety Data

• Hazardous Substances Data: 52121-06-9(Hazardous Substances Data)

Usage

Chemical class

Thiazole
Belonging to the thiazole class of chemicals, which is a group of organic compounds containing a bicyclic structure with a sulfur atom and a nitrogen atom.

Structural components

Nitro group, acetamide group
The presence of a nitro group (-NO2) and an acetamide group (-CONH2) in its structure, which contribute to its chemical properties and potential applications.

Potential medicinal properties

Antimicrobial, antiparasitic
2-[(2Z)-2-[(ethylcarbamoyl)imino]-5-nitro-1,3-thiazol-3(2H)-yl]-N,N-dipropylacetamide has shown potential as an antimicrobial and antiparasitic agent in preliminary studies, indicating its possible use in treating infections and parasitic infestations.
5. Application in pharmaceutical research and drug development
Commonly used in pharmaceutical research and drug development due to its potential medicinal properties, making it a subject of interest for further scientific investigation and possible therapeutic applications.

Upstream product

• 2315-37-9 2-chloro-N,N-dipropylacetamide 
• 139-94-6 1-ethyl-3-(5-nitro-thiazol-2-yl)-urea 
• 59721-11-8 2-bromo-N,N-dipropylacetamide 

Relevant articles and documents

Antiparasitic 5 nitrothiazoles and 5 nitro 4 thiazolines. 4

The synthesis and biological properties of some 2 heteroylimino 5 nitro 4 thiazoline 3 acetamides and some 1 (carbamoylmethyl) 1 (5 nitro 2 thiazolyl)ureas together with the corresponding ring N substituted [3 (carbamoylmethyl) 5 nitro 4 thiazolin 2 ylidene]ureas (I, R is NHR1) are described. The compounds were prepared by treatment of a DMF solution of the Na salt of the appropriate amide or urea with halo acetamides. Some of them have significant antischistosome properties.