52190-42-8

Basic information

• Product Name: Cyclooctanone, 2-(phenylthio)-
• CAS NO: 52190-42-8
• Molecular Formula: C14H18OS
• Molecular Weight: 234.362
• Mol File: 52190-42-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Cyclooctanone, 2-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclooctanone, 2-(phenylthio)-(52190-42-8)
• EPA Substance Registry System: Cyclooctanone, 2-(phenylthio)-(52190-42-8)

Safety Data

• Hazardous Substances Data: 52190-42-8(Hazardous Substances Data)

Upstream product

• 50338-42-6 (E)-1-trimethylsilyloxy-1-cyclooctene 
• 28833-59-2 C₂₆H₂₄N₂O₄S₄ 
• 108-98-5 thiophenol 
• 13307-76-1 [bis(phenylthio)methyl]lithium 
• 502-49-8 cycloactanone 
• 60595-16-6 (phenylthio)nitromethane 
• 931-59-9 benzenesulfenyl chloride 
• 882-33-7 diphenyldisulfane 
• 117543-17-6 1-(Nitro-phenylsulfanyl-methyl)-cycloheptanol 
• 57768-32-8 1-(Bis-phenylsulfanyl-methyl)-cycloheptanol 
• 50338-42-6 (cyclooct-1-enyloxy)-trimethylsilane 

Downstream Products

• 104260-89-1 2-Phenylsulfanyl-cyclooctanone oxime 
• 74546-10-4 2-Benzenesulfonyl-cyclooctanone 
• 55705-18-5 2-(phenylsulfinyl)cyclooctanone 
• 101704-33-0 (1R,2R)-1-Methyl-2-phenylsulfanyl-cyclooctanol 
• 101704-33-0 (1RS,2SR)-1-methyl-2-phenylthiocyclo-octanol 
• 101704-38-5 (Z)-1-Methyl-8-phenylsulfanyl-cyclooctene 
• 101704-26-1 (E)-1-Benzenesulfinylmethyl-cyclooctene 
• 125334-95-4 (E)-1-Methyl-2-phenylsulfanyl-cyclooctene 
• 125334-96-5 1-(Phenylthiomethyl)cyclooctene 
• 104301-68-0 1-Methylene-2-phenylsulfanyl-cyclooctane 
• 101704-22-7 1-(phenylthiomethyl)cyclo-octene 
• 74532-74-4 (E)-5-Benzenesulfonyl-3-methyl-cycloundec-2-enone 
• 74532-73-3 (Z)-5-Benzenesulfonyl-3-methyl-cycloundec-2-enone 
• 74532-64-2 2-Benzenesulfonyl-2-(2-trimethylsilanylmethyl-allyl)-cyclooctanone 

Relevant articles and documents

Disulfide-based metal-free α-sulfanylation of ketones

An eco-friendly methodology for the direct α-sulfanylation of ketones, has been developed. The procedure, based on the use of functionalized diaryldisulfides and catalyzed by d,l-proline, represents a mild and efficient approach for the preparation of α-arylthio-ketones.

Radical cyclizations of functionalized allenes

Substitution of P(O)Ph2, SOPh, and SO2Ph on an allene facilitates intramolecular radical addition to the central allene carbon to provide good yields of five-, six-, and seven-membered carbocycles.

A Ring Expansion of Cyclic Ketones to α-Phenylthio Ketones via Lewis Acid Mediated Denitration

The adducts of cyclic ketones with the lithium derivative of (phenylthio)nitromethane are readily rearranged to the ring expanded α-phenylthio ketones via aluminium chloride mediated denitration.