52197-13-4

Basic information

• Product Name: 5,6-bis(4-methylphenyl)pyrazine-2,3-dicarbonitrile
• CAS NO: 52197-13-4
• Molecular Formula: C₂₀H₁₄N₄
• Molecular Weight: 310.352
• Mol File: 52197-13-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 473.9°C at 760 mmHg
• Flash Point: 150°C
• Density: 1.26g/cm³
• Vapor Pressure: 3.77E-09mmHg at 25°C
• Refractive Index: 1.652
• CAS DataBase Reference: 5,6-bis(4-methylphenyl)pyrazine-2,3-dicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-bis(4-methylphenyl)pyrazine-2,3-dicarbonitrile(52197-13-4)
• EPA Substance Registry System: 5,6-bis(4-methylphenyl)pyrazine-2,3-dicarbonitrile(52197-13-4)

Safety Data

• Hazardous Substances Data: 52197-13-4(Hazardous Substances Data)

Upstream product

• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 
• 1187-42-4 diaminomaleonitrile 
• 54848-44-1 1,2-diamino-1,2-dicyanoethylene 
• 1218-89-9 4,4'-dimethylbenzoin 
• 18514-52-8 2,3-diaminomaleonitrile 

Relevant articles and documents

Silica gel an efficient catalyst for one-pot synthesis of pyrazines from ethylenediamine and 1, 2-diketones and their analogs

A straightforward one-pot synthesis of pyrazines from ethylenediamine and 1, 2-diketones/ α-hydroxy ketone/α-bromo ketone under solvent-free conditions at room temperature is described. This environmentally benign process has the edge on previous methods in respect of workup procedure, ease and cost of reaction, and use and generation of hazardous substances. The catalyst is recovered, characterized, and proved to be recyclable for successive four runs examined with appreciable conversions.

γ-Maghemite-silica nanocomposite: A green catalyst for diverse aromatic N-heterocycles

γ-Maghemite-silica nanocomposite has been applied as a green catalyst to synthesize variety of aromatic N-heterocycles under solvent free conditions. Characterization was done by modern analytical tools (UV, IR, AAS, DSC, EDXRF, powdered XRD, EPR, Mo?ssbauer and TEM). Mild reaction conditions and recyclability have made the present protocol both environmentally and economically viable.

Synthesis of potential antineoplastic agents. XXIV. Reaction of diaminomaleonitrile with 1,2 diones

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