52208-50-1Relevant articles and documents
PREPARATION OF NEW 2-CHLORO-5-FLUORO-6-(4-PHENYL-METHYLPIPERAZINYL)-4-TRIFLUOROMETHYL-3-NICOTINIC ACID
Remuzon, Philippe,Bouzard, Daniel,Jacquet, Jean-Pierre
, p. 431 - 434 (2007/10/02)
The nicotinic acid (15), which could be a key intermediate for novel potential antibacterial 1,8-naphthyridine-3-carboxylic acid analogues, was prepared initiating with construction of the pyridine nucleus by ethyl 2-fluoroacetate and ethyl 2-trifluoroacetate.
Method for preparing 2,5-dihalo- and 2,5,6-trihalopyridines
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, (2008/06/13)
A method for preparing 2,5-dihalo- and 2,5,6-trihalopyridines corresponding to the formula SPC1 Wherein each X independently represents chloro, fluoro or bromo and R represents hydrogen, chloro, fluoro or bromo which comprises reacting a halohydrazinopyridine of one of the formulas SPC2 With an excess of an aqueous alkali metal hydroxide in the presence of a reaction medium from the group consisting of loweralkanols of 1 to 4 carbon atoms and loweralkylglycols of 2 to 4 carbon atoms.