52553-03-4

Basic information

• Product Name: 5-methyl-5-phenyl-1,3-oxazolidin-2-one
• CAS NO: 52553-03-4
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.1998
• Mol File: 52553-03-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 387.5°C at 760 mmHg
• Flash Point: 188.1°C
• Density: 1.143g/cm³
• Vapor Pressure: 3.28E-06mmHg at 25°C
• Refractive Index: 1.531
• CAS DataBase Reference: 5-methyl-5-phenyl-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-5-phenyl-1,3-oxazolidin-2-one(52553-03-4)
• EPA Substance Registry System: 5-methyl-5-phenyl-1,3-oxazolidin-2-one(52553-03-4)

Safety Data

• Hazardous Substances Data: 52553-03-4(Hazardous Substances Data)

Upstream product

• 81467-25-6 3-(2-Hydroxy-2-phenylpropyl)-1,4,2-dioxazol-5-on 
• 17643-24-2 (+/-)-1-amino-2-phenylpropan-2-ol 
• 530-62-1 1,1'-carbonyldiimidazole 
• 98-86-2 acetophenone 
• 127462-20-8 2-phenyl-2-trimethylsilyloxypropanenitrile 
• 108-86-1 bromobenzene 
• 100-58-3 phenylmagnesium bromide 
• 7133-68-8 3-phenylbutane-1,3-diol 
• 98-83-9 isopropenylbenzene 

Relevant articles and documents

Practical Synthetic Procedures for the Iron-Catalyzed Intermolecular Olefin Aminohydroxylation Using Functionalized Hydroxylamines

A set of practical synthetic procedures for the iron-catalyzed intermolecular olefin aminohydroxylation reactions in gram scale is reported. In these transformations, a bench-stable functionalized hydroxylamine is applied as the amination reagent. This method is compatible with a broad range of synthetically valuable olefins including those that are incompatible with the existing aminohydroxylation methods. It also provides valuable amino alcohol building blocks with regio- and stereochemical arrays that are complementary to known methods.

Synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols or 3-amino alcohols using iodobenzene dichloride and sodium azide

A general and efficient method for the synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols and 3-amino alcohols has been developed using the same reagent combination of iodobenzene dichloride (PhICl2) and sodium azide (NaN3).

Cyclic Carbonylation of 3-Hydroxycarbohydroxamic Acids with 1,1'-Carbonyldiimidazole

The reaction of 3-hydroxycarbohydroxamic acids 3 with 1,1'-carbonyldiimidazole produces as a function of the substitution of 3 heterocycles of type 1, 4, and 5.In the presence of imidazole the 3-(2-hydroxyalkyl)-1,4,2-dioxazol-5-ones 1 undergo rearrangeme