52559-90-7

Basic information

• Product Name: HEXAETHYLENE GLYCOL DICHLORIDE
• Synonyms: HEXAETHYLENE GLYCOL DICHLORIDE;Bis[2-[2-(2-chloroethoxy)ethoxy]ethyl]ether
• CAS NO: 52559-90-7
• Molecular Formula: C₁₂H₂₄Cl₂O₅
• Molecular Weight: 319.22
• Mol File: 52559-90-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: -12 °C
• Boiling Point: 162 °C/0.3 mmHg
• Appearance: /
• Refractive Index: 1.47
• CAS DataBase Reference: HEXAETHYLENE GLYCOL DICHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: HEXAETHYLENE GLYCOL DICHLORIDE(52559-90-7)
• EPA Substance Registry System: HEXAETHYLENE GLYCOL DICHLORIDE(52559-90-7)

Safety Data

• Hazardous Substances Data: 52559-90-7(Hazardous Substances Data)

Usage

General Description

Hexaethylene glycol dichloride, also known as 6-chloro-6,9-dioxatetradecane-1,14-diol, is a chemical compound with the molecular formula C10H20Cl2O4. It is a colorless liquid at room temperature and is primarily used as a reactive intermediate in the production of various polymers and surfactants. It is also used in the synthesis of organic compounds and in the manufacture of agrochemicals. Hexaethylene glycol dichloride is a versatile compound with a wide range of industrial applications, making it an important chemical in the manufacturing and production of various products. However, it is important to handle this compound with care as it is toxic and can cause irritation to the skin and eyes.

Upstream product

• 2615-15-8 pentaethylene glycol 

Downstream Products

• 4435-21-6 1,17-dibutoxy-3,6,9,12,15-pentaoxa-heptadecane 
• 1072-40-8 2,5,8,11,14,17,20-heptaoxahenicosane 
• 5117-19-1 octaethylene glycol 
• 80900-28-3 N-cyano monoaza 18-crown-6 
• 143062-17-3 (17S,18R)-17,18-Diphenyl-1,4,7,10,13-pentaoxa-16,19-diaza-cyclohenicosane 
• 143029-12-3 (17R,18R)-17,18-Diphenyl-1,4,7,10,13-pentaoxa-16,19-diaza-cyclohenicosane 
• 122039-74-1 1,17-bis(diphenylphosphinoyl)-3,6,9,12,15-pentaoxaheptadecane 
• 84649-38-7 1,17-bis(p-nitrophenoxy)-3,6,9,12,15-pentaoxaheptadecane 
• 135617-39-9 4,4'-<(3,6,9,12,15-pentaoxaheptadecamethylene)bis(phenylphosphinylidene)>bisbenzo-15-crown-5 
• 132054-13-8 1,21-bis(diphenylphosphinoyl)-2,5,8,11,14,17,20-hexaoxaheneicosane 
• 4445-03-8 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51-heptadecaoxa-tripentacontane-1,53-diol 
• 84649-40-1 1,17-bis(p-aminophenoxy)-3,6,9,12,15-pentaoxaheptadecane 
• 72236-26-1 2-(2-(2-(2-(2-(2-aminoethoxy)-ethoxy)-ethoxy)-ethoxy)-ethoxy)-ethyl amine 

Relevant articles and documents

Crown-annelated oligothiophenes as model compounds for molecular actuation

Crown-annelated quater- (4T) and sexithiophenes (6T) with oligooxyethylene chains of various lengths attached at the 3-positions of the terminal thiophene rings have been synthesized. Analysis of the cation-binding properties of the macrocycles by 1H NMR and UV-vis spectroscopy reveals the formation of a 1:1 complex with Ba2+, Sr2+, or Pb2+ and shows that cation complexation results in a conformational transition in the π-conjugated system. Theoretical analysis of this process by density functional methods predicts that this conformational transition results in a narrowing of the highest occupied-lowest unoccupied molecular orbital gap of the conjugated system with a decrease of the redox potentials (E01 and E02) associated with the formation of the 4T cation radical and dication. Cyclic voltammetry shows that, depending on the binding constant, the presence of metal cation produces a negative or a positive shift of E01 while E02 always shifts negatively. This unusual behavior is discussed in terms of interplay between electrostatic interactions and conformational changes associated with cation binding.

Alkylated styrenes as prodrugs to COX-2 inhibitors

The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. STR1 The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.

Ion selective fluorogenic reagents

Novel fluorogenic ionophores have been synthesized which selectively bind ions such as potassium and sodium, even in neutral aqueous and alcoholic media and respond to such binding by fluorescence quenching or enhancement. These ionophores are ideal for the selective and direct determination of ions in biological or environmental samples and the like. The ionophores are also suitable for incorporation into fiber optic-based sensors for the continuous in vivo or in vitro monitoring of metal ions in blood or other biological fluids.