52711-30-5Relevant articles and documents
Phthalide synthesis through dehydrogenated lactonization of the C(sp3)-H bond by photoredox catalysis
Cai, Shunyou,Cai, Zhixiong,Chen, Shanyi,Huang, Mingqiang,Lai, Qihong,Lin, Yulin,Liu, Chao,Liu, Hui
supporting information, p. 8212 - 8216 (2021/10/29)
A practical and efficient method is established for the direct oxidative lactonization of the C(sp3)-H bonds relying on visible-light-induced photoredox catalysis. This protocol expediently allows the delivery of diverse phthalides using oxygen as the sole terminal oxidant under metal-free conditions at room temperature. Notably, the choice of an appropriate hydrogen atom transfer (HAT) cocatalyst is revealed to be critical for the success of this process.
Highly selective and scalable fullerene-cation-mediated synthesis accessing cyclo[60]fullerenes with five-membered carbon ring and their application to perovskite solar cells
Lin, Hao-Sheng,Jeon, Il,Chen, Yingqian,Yang, Xiao-Yu,Nakagawa, Takafumi,Maruyama, Shigeo,Manzhos, Sergei,Matsuo, Yutaka
, p. 8432 - 8439 (2019/10/16)
Cyclo[60]fullerenes are widely used in many applications including photovoltaic devices owing to their high electron affinity and mobility for an organic molecule. However, their synthesis has been limited to certain derivatives with low yields. In this work, a fullerene-cation-mediated synthesis, accessing a new class of five-membered carbon ring cyclo[60]fullerenes with high yields of up to 93% is showcased. This method utilizes aryl[60]fullerene cations, ArC60 +, as intermediates, which are generated in situ by heating the aryl[60]fullerenyl dimers in the presence of CuBr2. In addition, five-membered carbon ring cyclo[60]fullerenes display excellent device applicability when they are used in perovskite solar cells as over-coating layers of electron-transporting layers. A power conversion efficiency of 20.7% is achieved owing to the favorable energy alignment, optimized substrate design, and electrochemical stability of the five-membered carbon ring fullerenes.
Diselenides and benzisoselenazolones as antiproliferative agents and glutathione-S-transferase inhibitors
Krasowska, Dorota,Iraci, Nunzio,Santi, Claudio,Drabowicz, Józef,Cieslak, Marcin,Ka?mierczak-Barańska, Julia,Palomba, Martina,Królewska-Golińska, Karolina,Magiera, Jakub,Sancineto, Luca
, (2019/08/20)
A series of variously functionalized selenium-containing compounds were purposely synthesized and evaluated against a panel of cancer cell lines. Most of the compounds showed an interesting cytotoxicity profile with compound 5 showing a potent activity on MCF7 cells. The ethyl amino derivative 5 acts synergistically with cis-platin and inhibits the GST enzyme with a potency that well correlates with the cytotoxicity observed in MCF7 cells. A computational analysis suggests a possible binding mode on the GST enzyme. As the main outcome of the present study, the ethyl amino derivative 5 emerged as a valid lead compound for further, future developments.