52751-69-6Relevant articles and documents
Novel phenolic compound and preparation method and application thereof
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Paragraph 0081-0087, (2020/09/09)
The invention provides a novel phenolic compound and a preparation method and application thereof. The chemical general formula of the novel phenolic compound is as shown in formula (1), and R is Br,Cl or F. According to the novel phenolic compound, the growth of gram-positive bacteria can be obviously inhibited, the minimum inhibitory concentration on staphylococcus aureus, bacillus and methicillin-resistant staphylococcus aureus is 1-4mu g/mL, the drug resistance is not generated under long-time low-dose exposure, and the compound can be used as a gram-positive bacteria antibacterial agentand has a good antibacterial effect.
HIV integrase inhibitors
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, (2008/06/13)
Certain six-membered aromatic and heteroaromatic-dioxobutyric acid derivatives are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment