52767-61-0

Basic information

• Product Name: ethylene bis(hydroxyacetate)
• Synonyms: ethylene bis(hydroxyacetate);Bis(2-hydroxyacetic acid)1,2-ethanediyl ester;Acetic acid, 2-hydroxy-, 1,1'-(1,2-ethanediyl) ester;Acetic acid, hydroxy-, 1,2-ethanediyl ester;Einecs 258-165-1
• CAS NO: 52767-61-0
• Molecular Formula: C₆H₁₀O₆
• Molecular Weight: 178.14
• EINECS: 258-165-1
• Mol File: 52767-61-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 328.1°Cat760mmHg
• Flash Point: 136.5°C
• Appearance: /
• Density: 1.375g/cm³
• Vapor Pressure: 1.46E-05mmHg at 25°C
• Refractive Index: 1.474
• PKA: 12.54±0.10(Predicted)
• CAS DataBase Reference: ethylene bis(hydroxyacetate)(CAS DataBase Reference)
• NIST Chemistry Reference: ethylene bis(hydroxyacetate)(52767-61-0)
• EPA Substance Registry System: ethylene bis(hydroxyacetate)(52767-61-0)

Safety Data

• Hazardous Substances Data: 52767-61-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H10O6/c7-3-5(9)11-1-2-12-6(10)4-8/h7-8H,1-4H2

Upstream product

• 96-35-5 glycolic acid methyl ester 
• 107-21-1 ethylene glycol 
• 31517-02-9 anhydrocarboxyglycolic acid 
• 5271-60-3 1,1,6,6-tetra-n-butyl-1,6-distanna-2,5,7,10-tetraoxacyclodecane 
• 79-14-1 glycolic Acid 

Relevant articles and documents

NOVEL INSERTION REACTIONS INTO CYCLIC TIN-OXYGEN COMPOUNDS

A series of novel insertion reactions of cyclic carbonyl compounds into cyclic tin-oxygen compounds is described.Cyclic carboxycarbonate (1) and isatoic anhydride (4) react with cyclic stannoxane (2) to give the acyclic diester (3) and diamide (5) respectively.Cyclic anhydrides derived from aspartic and glutamic acids (6, 7, 10 and 11) react with 2 to give the macrocyclic tetralactones (8) and (9), and dilactones (12) and (13) respectively.These reactions may be of general synthetic value because of their high specificity.They lead either to singly acylated, acyclic products (3 and 5), or to regiospecific macrocyclic products (8, 9, 12 and 13) in preference to oligomers.The high specificity of these reactions is attributed to: (i) the dual function of the tin element, which may act either as activating group or as protecting group, and (ii) the occurrence of non-covalent transannular interactions between tin and oxygen in the cyclic stannoxane 2.

Method for producing alpha - hydroxycarboxylate

The present invention provides a process for more efficiently producing an α-hydroxycarboxylic acid ester wherein side reactions due to the α-hydroxycarboxylic acid ester are inhibited or prevented in comparison with prior art production processes. The invention provides a process for producing an α-hydroxycarboxylic acid ester comprising Steps 1 to 3: Step 1. reacting, in the presence of oxygen, (i) a 1,2-diol with a 1,2-diol or (ii) a 1,2-diol with an alcohol to obtain a reaction product containing an α-hydroxycarboxylic acid ester; Step 2. separating the α-hydroxycarboxylic acid ester from the reaction product obtained in Step 1 by distillation under reduced pressure; and Step 3. feeding Step 1 with a mixture obtained by partially or entirely removing water from the reaction product, wherein the mixture contains an unreacted 1,2-diol and/or alcohol.