52831-71-7

Basic information

• Product Name: 7-chloro-3-(dimethylamino)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• CAS NO: 52831-71-7
• Molecular Formula: C₁₇H₁₆ClN₃O
• Molecular Weight: 313.7814
• Mol File: 52831-71-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 481.6°C at 760 mmHg
• Flash Point: 245.1°C
• Density: 1.27g/cm³
• Vapor Pressure: 1.96E-09mmHg at 25°C
• Refractive Index: 1.638
• CAS DataBase Reference: 7-chloro-3-(dimethylamino)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-chloro-3-(dimethylamino)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one(52831-71-7)
• EPA Substance Registry System: 7-chloro-3-(dimethylamino)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one(52831-71-7)

Safety Data

• Hazardous Substances Data: 52831-71-7(Hazardous Substances Data)

Upstream product

• 124-40-3 dimethyl amine 
• 604-75-1 oxazepam 

Relevant articles and documents

Synthesis of 3-Substituted-amino/aroyloxy-7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-ones as Possible Anxiolytics

Ten new 3-substituted-amino/aroyloxy-7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-ones were synthesised and tested for their acute toxicity, effect on gross behaviour and anxiolytic activity using antihypoxia and antimetrazole tests in mice.At 1/5th ALD50, two compounds, one with a morpholino group and the other with a 4-methoxybenzoyloxy group at 3-position exhibited maximum antimetrazole activity similar to oxazepam and also produced significant increase of survival time in antihypoxia test which was comparable to oxazepam.

Heterocycles. X. Synthesis and reactions of 1,4,5-benzotriazocinium salts

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